catharanthine

Base Information

• Chemical Name: catharanthine
• CAS No.: 1212401-29-0
• Molecular Formula: C₂₁H₂₄N₂O₂
• Molecular Weight: 336.434

Synonyms:catharanthine

Chemical Property of catharanthine

Chemical Property:

Purity/Quality:

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Technology Process of catharanthine

There total 1 articles about catharanthine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3',4'-anhydrovinblastine → hoerhammericine (19459-04-2,61825-77-2,109063-93-6,109063-94-7) + 19-epivindolinine (27773-39-3,86116-70-3,106356-44-9) + catharanthine (1212401-29-0) + ajmalicine (483-04-5)

Guidance literature:

at 27 ℃; Yield given. Further byproducts given. Yields of byproduct given; C_. roseus 200GW cell line;

DOI:10.1016/S0040-4020(01)88620-8

Reference yield:

3-demethoxycarbonyl-3-(benzoylamino)ethylvindoline + catharanthine (1212401-29-0) → 3-demethoxycarbonyl-3-(benzoylamino)ethylanhydrovinblastine

Guidance literature:

3-demethoxycarbonyl-3-(benzoylamino)ethylvindoline; catharanthine; With sodium hydrogen sulfate; ammonium cerium (IV) nitrate; In 2,2,2-trifluoroethanol; water; at 20 ℃; for 8h; Inert atmosphere; Darkness;

With ammonium hydroxide; sodium tetrahydroborate; In 2,2,2-trifluoroethanol; water; at 0 ℃; for 0.5h; Inert atmosphere; Darkness;

DOI:10.1016/j.bmcl.2011.10.114

Reference yield:

3-demethoxycarbonyl-3-(4'-toluoylamino)ethylvindoline + catharanthine (1212401-29-0) → 3-demethoxycarbonyl-3-(4'-toluoylamino)ethylanhydrovinblastine

Guidance literature:

3-demethoxycarbonyl-3-(4'-toluoylamino)ethylvindoline; catharanthine; With sodium hydrogen sulfate; ammonium cerium (IV) nitrate; In 2,2,2-trifluoroethanol; water; at 20 ℃; for 8h; Inert atmosphere; Darkness;

With ammonium hydroxide; sodium tetrahydroborate; In 2,2,2-trifluoroethanol; water; at 0 ℃; for 0.5h; Inert atmosphere; Darkness;

DOI:10.1016/j.bmcl.2011.10.114

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