(2S,3R,4E)-3-benzoyloxy-2-hexadecanoylamino-1-[2-O-(3,3-di-tert-butyloxycarbonylpropyl)-3-O-benzoyl-α-D-galactopyranosyloxy]-4-octadecene

Base Information

Chemical Name:(2S,3R,4E)-3-benzoyloxy-2-hexadecanoylamino-1-[2-O-(3,3-di-tert-butyloxycarbonylpropyl)-3-O-benzoyl-α-D-galactopyranosyloxy]-4-octadecene
CAS No.:206856-98-6
Molecular Formula:C₆₇H₁₀₇NO₁₄
Molecular Weight:1150.58
Hs Code.:

Synonyms:(2S,3R,4E)-3-benzoyloxy-2-hexadecanoylamino-1-[2-O-(3,3-di-tert-butyloxycarbonylpropyl)-3-O-benzoyl-α-D-galactopyranosyloxy]-4-octadecene

Suppliers and Price of (2S,3R,4E)-3-benzoyloxy-2-hexadecanoylamino-1-[2-O-(3,3-di-tert-butyloxycarbonylpropyl)-3-O-benzoyl-α-D-galactopyranosyloxy]-4-octadecene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3R,4E)-3-benzoyloxy-2-hexadecanoylamino-1-[2-O-(3,3-di-tert-butyloxycarbonylpropyl)-3-O-benzoyl-α-D-galactopyranosyloxy]-4-octadecene

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3R,4E)-3-benzoyloxy-2-hexadecanoylamino-1-[2-O-(3,3-di-tert-butyloxycarbonylpropyl)-3-O-benzoyl-α-D-galactopyranosyloxy]-4-octadecene

There total 13 articles about (2S,3R,4E)-3-benzoyloxy-2-hexadecanoylamino-1-[2-O-(3,3-di-tert-butyloxycarbonylpropyl)-3-O-benzoyl-α-D-galactopyranosyloxy]-4-octadecene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 206856-97-5
(2S,3R,4E)-3-benzoyloxy-2-hexadecanoylamino-1-[2-O-(3,3-di-tert-butyloxycarbonylpropyl)-3-O-benzoyl-4,6-O-benzylidene-α-D-galactopyranosyloxy]-4-octadecene

: 206856-98-6
(2S,3R,4E)-3-benzoyloxy-2-hexadecanoylamino-1-[2-O-(3,3-di-tert-butyloxycarbonylpropyl)-3-O-benzoyl-α-D-galactopyranosyloxy]-4-octadecene

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 0 ℃;
DOI:10.1016/S0968-0896(01)00015-3

Reference yield:

: 172146-95-1
ethyl 3,4-O-isopropylidene-1-thio-β-D-galactopyranoside

: 206856-98-6
(2S,3R,4E)-3-benzoyloxy-2-hexadecanoylamino-1-[2-O-(3,3-di-tert-butyloxycarbonylpropyl)-3-O-benzoyl-α-D-galactopyranosyloxy]-4-octadecene

Guidance literature:: Multi-step reaction with 12 steps

1.1: 100 percent / pyridine / 5 h

2.1: 92 percent / NaH / dimethylformamide / 1 h

3.1: 80 percent / LiAlH₄ / tetrahydrofuran / 2 h

4.1: 97 percent / Et₃N / CH₂Cl₂ / 0.5 h

5.1: NaH; KI / dimethylformamide; tetrahydrofuran / 12 h / 65 °C

6.1: 0.069 g / Bu₄NF / tetrahydrofuran / 22 °C

7.1: 93 percent / aq. HCl / tetrahydrofuran / 12 h / 22 °C

8.1: 89 percent / p-toluenesulfonic acid / acetonitrile / 22 °C

9.1: 99 percent / 4-dimethylaminopyridine / CH₂Cl₂; pyridine / 22 °C

10.1: 2,6-di-tert-butyl-4-methylpyridine / dioxane / 22 °C

10.2: 64 percent / dimethyl(methylthio)sulfonium triflate / dioxane

11.1: H₂S / H₂O; pyridine

11.2: 92 percent / aq. NaOAc / tetrahydrofuran / 22 °C

12.1: 83 percent / aq. CF₃COOH / CH₂Cl₂ / 0 °C

With hydrogenchloride; dmap; lithium aluminium tetrahydride; 2,6-di-tert-butyl-4-methylpyridine; hydrogen sulfide; tetrabutyl ammonium fluoride; sodium hydride; toluene-4-sulfonic acid; triethylamine; trifluoroacetic acid; potassium iodide; In tetrahydrofuran; 1,4-dioxane; pyridine; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/S0968-0896(01)00015-3

Reference yield:

: 56245-60-4,686299-00-3
ethyl 1-thio-β-D-galactopyranoside

: 206856-98-6
(2S,3R,4E)-3-benzoyloxy-2-hexadecanoylamino-1-[2-O-(3,3-di-tert-butyloxycarbonylpropyl)-3-O-benzoyl-α-D-galactopyranosyloxy]-4-octadecene

Guidance literature:: Multi-step reaction with 13 steps

1.1: 87 percent / p-toluenesulfonic acid / 24 h / 22 °C

2.1: 100 percent / pyridine / 5 h

3.1: 92 percent / NaH / dimethylformamide / 1 h

4.1: 80 percent / LiAlH₄ / tetrahydrofuran / 2 h

5.1: 97 percent / Et₃N / CH₂Cl₂ / 0.5 h

6.1: NaH; KI / dimethylformamide; tetrahydrofuran / 12 h / 65 °C

7.1: 0.069 g / Bu₄NF / tetrahydrofuran / 22 °C

8.1: 93 percent / aq. HCl / tetrahydrofuran / 12 h / 22 °C

9.1: 89 percent / p-toluenesulfonic acid / acetonitrile / 22 °C

10.1: 99 percent / 4-dimethylaminopyridine / CH₂Cl₂; pyridine / 22 °C

11.1: 2,6-di-tert-butyl-4-methylpyridine / dioxane / 22 °C

11.2: 64 percent / dimethyl(methylthio)sulfonium triflate / dioxane

12.1: H₂S / H₂O; pyridine

12.2: 92 percent / aq. NaOAc / tetrahydrofuran / 22 °C

13.1: 83 percent / aq. CF₃COOH / CH₂Cl₂ / 0 °C

With hydrogenchloride; dmap; lithium aluminium tetrahydride; 2,6-di-tert-butyl-4-methylpyridine; hydrogen sulfide; tetrabutyl ammonium fluoride; sodium hydride; toluene-4-sulfonic acid; triethylamine; trifluoroacetic acid; potassium iodide; In tetrahydrofuran; 1,4-dioxane; pyridine; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/S0968-0896(01)00015-3