Benzoic acid (1R,2S,3S,4S)-2-(tert-butyl-dimethyl-silanyloxy)-3,4-dihydroxy-4-methyl-cyclopentyl ester

Base Information

Chemical Name:Benzoic acid (1R,2S,3S,4S)-2-(tert-butyl-dimethyl-silanyloxy)-3,4-dihydroxy-4-methyl-cyclopentyl ester
CAS No.:99474-65-4
Molecular Formula:C₁₉H₃₀O₅Si
Molecular Weight:366.53
Hs Code.:

Synonyms:Benzoic acid (1R,2S,3S,4S)-2-(tert-butyl-dimethyl-silanyloxy)-3,4-dihydroxy-4-methyl-cyclopentyl ester

Suppliers and Price of Benzoic acid (1R,2S,3S,4S)-2-(tert-butyl-dimethyl-silanyloxy)-3,4-dihydroxy-4-methyl-cyclopentyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Benzoic acid (1R,2S,3S,4S)-2-(tert-butyl-dimethyl-silanyloxy)-3,4-dihydroxy-4-methyl-cyclopentyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Benzoic acid (1R,2S,3S,4S)-2-(tert-butyl-dimethyl-silanyloxy)-3,4-dihydroxy-4-methyl-cyclopentyl ester

There total 8 articles about Benzoic acid (1R,2S,3S,4S)-2-(tert-butyl-dimethyl-silanyloxy)-3,4-dihydroxy-4-methyl-cyclopentyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 99474-64-3
C₂₆H₃₄O₆Si

: 99474-65-4
Benzoic acid (1R,2S,3S,4S)-2-(tert-butyl-dimethyl-silanyloxy)-3,4-dihydroxy-4-methyl-cyclopentyl ester

Guidance literature:: With potassium carbonate; In methanol; at 0 ℃; for 12h;
DOI:10.1016/S0040-4039(00)89245-X

Reference yield:

: 65457-77-4
4-<(1,1'-dimethylbenzyl)oxy>-2-cyclopentenone

: 99474-65-4
Benzoic acid (1R,2S,3S,4S)-2-(tert-butyl-dimethyl-silanyloxy)-3,4-dihydroxy-4-methyl-cyclopentyl ester

Guidance literature:: Multi-step reaction with 7 steps

1: 86 percent / tetrahydrofuran / 1 h / -30 °C

2: 85 percent / MCPBA / CH₂Cl₂ / 20 h / Ambient temperature

3: 2.) Tl(ONO₂)3*3H₂O / 1.) hydrolysis; 2.) CH₂Cl₂, r.t., 2.5 h

4: Et₃N / acetonitrile / 2 h / Ambient temperature

5: 92 percent / Zn, AcOH / 1 h / Ambient temperature

6: 98 percent / imidazole, DMAP / CH₂Cl₂ / 6 h / Ambient temperature

7: 85 percent / K₂CO₃ / methanol / 12 h / 0 °C

With 1H-imidazole; dmap; potassium carbonate; acetic acid; triethylamine; 3-chloro-benzenecarboperoxoic acid; thallium(III) nitrate; zinc; In tetrahydrofuran; methanol; dichloromethane; acetonitrile;
DOI:10.1016/S0040-4039(00)89245-X

Reference yield:

: 99474-60-9
(1R,2R,3S,4S)-1-Methyl-3-nitrooxy-cyclopentane-1,2,4-triol

: 99474-65-4
Benzoic acid (1R,2S,3S,4S)-2-(tert-butyl-dimethyl-silanyloxy)-3,4-dihydroxy-4-methyl-cyclopentyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: Et₃N / acetonitrile / 2 h / Ambient temperature

2: 92 percent / Zn, AcOH / 1 h / Ambient temperature

3: 98 percent / imidazole, DMAP / CH₂Cl₂ / 6 h / Ambient temperature

4: 85 percent / K₂CO₃ / methanol / 12 h / 0 °C

With 1H-imidazole; dmap; potassium carbonate; acetic acid; triethylamine; zinc; In methanol; dichloromethane; acetonitrile;
DOI:10.1016/S0040-4039(00)89245-X