(4S,5R,E)-6-hydroxy-5-benzyloxy-4-acetyloxy-2-hexenal trimethylenedithioacetal

Base Information

Chemical Name:(4S,5R,E)-6-hydroxy-5-benzyloxy-4-acetyloxy-2-hexenal trimethylenedithioacetal
CAS No.:263388-30-3
Molecular Formula:C₁₈H₂₄O₄S₂
Molecular Weight:368.518
Hs Code.:

Synonyms:(4S,5R,E)-6-hydroxy-5-benzyloxy-4-acetyloxy-2-hexenal trimethylenedithioacetal

Suppliers and Price of (4S,5R,E)-6-hydroxy-5-benzyloxy-4-acetyloxy-2-hexenal trimethylenedithioacetal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (4S,5R,E)-6-hydroxy-5-benzyloxy-4-acetyloxy-2-hexenal trimethylenedithioacetal

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (4S,5R,E)-6-hydroxy-5-benzyloxy-4-acetyloxy-2-hexenal trimethylenedithioacetal

There total 6 articles about (4S,5R,E)-6-hydroxy-5-benzyloxy-4-acetyloxy-2-hexenal trimethylenedithioacetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 263388-29-0
(4S,5R,E)-6-(4-methoxytrityloxy)-5-benzyloxy-5-acetyloxy-2-hexenal trimethylenedithioacetal

: 263388-30-3
(4S,5R,E)-6-hydroxy-5-benzyloxy-4-acetyloxy-2-hexenal trimethylenedithioacetal

Guidance literature:: With hydrogenchloride; In tetrahydrofuran; at 20 ℃; for 2h;
DOI:10.1080/00397910008087311

Reference yield: 17.0%

: 263388-26-7
(4S,5R,E)-4,6-diacetyloxy-5-benzyloxy-2-hexenal trimethylenedithioacetal

: 263388-27-8
(4S,5R,E)-4,6-dihydroxy-5-benzyloxy-2-hexenal trimethylenedithioacetal

: 263388-30-3
(4S,5R,E)-6-hydroxy-5-benzyloxy-4-acetyloxy-2-hexenal trimethylenedithioacetal

Guidance literature:: With sodium methylate; In methanol; at 20 ℃; for 18h;
DOI:10.1080/00397910008087311

Reference yield:

: 263388-25-6
(4S,5R,E)-4,6-diacetyloxy-5-hydroxy-2-hexenal trimethylenedithio acetal

: 263388-30-3
(4S,5R,E)-6-hydroxy-5-benzyloxy-4-acetyloxy-2-hexenal trimethylenedithioacetal

Guidance literature:: Multi-step reaction with 5 steps

1: 72 percent / NaH; Bu₄NI / dimethylformamide / 0 - 20 °C

2: 50 percent / NaOCH₃ / methanol / 48 h / 20 °C

3: 63 percent / pyridine / 24 h / 20 °C

4: 46 percent / pyridine / 72 h / 20 °C

5: 76 percent / 0.01N HCl / tetrahydrofuran / 2 h / 20 °C

With hydrogenchloride; sodium methylate; tetra-(n-butyl)ammonium iodide; sodium hydride; In tetrahydrofuran; pyridine; methanol; N,N-dimethyl-formamide; 1: Substitution / 2: Deacetylation / 3: Substitution / 4: Acetylation / 5: Hydrolysis;
DOI:10.1080/00397910008087311