trans-<2-(1',3'-dithian-2'-yl)cyclopentyl>diphenylphosphine oxide

Base Information

• Chemical Name: trans-<2-(1',3'-dithian-2'-yl)cyclopentyl>diphenylphosphine oxide
• CAS No.: 130866-01-2
• Molecular Formula: C₂₁H₂₅OPS₂
• Molecular Weight: 388.535
• Mol file: 130866-01-2.mol

Synonyms:trans-<2-(1',3'-dithian-2'-yl)cyclopentyl>diphenylphosphine oxide

Chemical Property of trans-<2-(1',3'-dithian-2'-yl)cyclopentyl>diphenylphosphine oxide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of trans-<2-(1',3'-dithian-2'-yl)cyclopentyl>diphenylphosphine oxide

There total 2 articles about trans-<2-(1',3'-dithian-2'-yl)cyclopentyl>diphenylphosphine oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

2-lithio-1,3-dithiane (36049-90-8) + (cyclopent-2-enyl)-diphenylphosphine oxide (38868-18-7) → trans-<2-(1',3'-dithian-2'-yl)cyclopentyl>diphenylphosphine oxide (130866-01-2)

Guidance literature:

With N,N,N,N,-tetramethylethylenediamine; at -40 - -20 ℃; for 3h;

DOI:10.1016/S0957-4166(00)86121-2

Reference yield:

1,3 dithiane (505-23-7) + (1-cyclopentenyl)triphenylphosphonium perchlorate → trans-<2-(1',3'-dithian-2'-yl)cyclopentyl>diphenylphosphine oxide (130866-01-2)

Guidance literature:

With sodium hydroxide; n-butyllithium; Multistep reaction; 1.) THF, -40 to -20 deg C, 3h, 2.) methanol, water, reflux, 7h;

DOI:10.1016/S0040-4039(00)97502-6

Reference yield: 99.0%

trans-<2-(1',3'-dithian-2'-yl)cyclopentyl>diphenylphosphine oxide (130866-01-2) → trans-(2-formylcyclopentyl)diphenylphosphine oxide (130866-03-4)

Guidance literature:

With ammonium cerium(IV) nitrate; In acetone; Ambient temperature;

DOI:10.1016/S0957-4166(00)86121-2

upstream raw materials:

1,3 dithiane

2-lithio-1,3-dithiane

(cyclopent-2-enyl)-diphenylphosphine oxide

Downstream raw materials:

trans-(2-formylcyclopentyl)diphenylphosphine oxide

(1S,2R)-2-Diphenylphosphanyl-cyclopentanecarboxylic acid