(4R,5R)-2--5-O-benzyl-4-O-benzylmethyl-1,4,5,6-tetrahydropyrimidine

Base Information

• Chemical Name: (4R,5R)-2--5-O-benzyl-4-O-benzylmethyl-1,4,5,6-tetrahydropyrimidine
• CAS No.: 161290-48-8
• Molecular Formula: C₃₁H₄₁N₃O₇
• Molecular Weight: 567.682

Synonyms:(4R,5R)-2--5-O-benzyl-4-O-benzylmethyl-1,4,5,6-tetrahydropyrimidine

Chemical Property of (4R,5R)-2--5-O-benzyl-4-O-benzylmethyl-1,4,5,6-tetrahydropyrimidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4R,5R)-2--5-O-benzyl-4-O-benzylmethyl-1,4,5,6-tetrahydropyrimidine

There total 2 articles about (4R,5R)-2--5-O-benzyl-4-O-benzylmethyl-1,4,5,6-tetrahydropyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

N-<3-amino-2,4-di-O-benzyl-1,3-dideoxy-D-treityl>-N'-<6-deoxy-1,2:3,5-di-O-isopropylidene-α-D-glucofuranosyl>-thiourea → (4R,5R)-2--5-O-benzyl-4-O-benzylmethyl-1,4,5,6-tetrahydropyrimidine (161290-48-8)

Guidance literature:

With lead(II) oxide; In ethanol; for 14h; Heating;

DOI:10.1016/S0957-4166(00)86302-8

Reference yield:

1,3-Diamino-2,4-di-O-benzyl-1,3-didesoxy-D-threitol (163211-53-8) → (4R,5R)-2--5-O-benzyl-4-O-benzylmethyl-1,4,5,6-tetrahydropyrimidine (161290-48-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 80 percent / CH₂Cl₂ / 3 h / Ambient temperature

2: 75 percent / PbO / ethanol / 14 h / Heating

With lead(II) oxide; In ethanol; dichloromethane;

DOI:10.1016/S0957-4166(00)86302-8

Reference yield:

(4R,5R)-2--5-O-benzyl-4-O-benzylmethyl-1,4,5,6-tetrahydropyrimidine (161290-48-8) → (4R,5R)-2--5-O-benzyl-4-O-benzylmethyl-1,4,5,6-tetrahydropyrimidine

Guidance literature:

With trifluoroacetic acid; at 60 ℃; for 3h;

DOI:10.1016/S0957-4166(00)86302-8

upstream raw materials:

1,3-Diamino-2,4-di-O-benzyl-1,3-didesoxy-D-threitol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 161290-48-8 (4R,5R)-2--5-O-benzyl-4-O-benzylmethyl-1,4,5,6-tetrahydropyrimidine

Send

Send

Metric Ton KG G Pound L ML

Send

Send