Carbamic acid, (3-methyl-2-oxobutyl)-, 1,1-dimethylethyl ester (9CI)

Base Information

• Chemical Name: Carbamic acid, (3-methyl-2-oxobutyl)-, 1,1-dimethylethyl ester (9CI)
• CAS No.: 388113-93-7
• Molecular Formula: C₁₀H₁₉NO₃
• Molecular Weight: 201.266
• Mol file: 388113-93-7.mol

Synonyms:Carbamic acid, (3-methyl-2-oxobutyl)-, 1,1-dimethylethyl ester (9CI)

Chemical Property of Carbamic acid, (3-methyl-2-oxobutyl)-, 1,1-dimethylethyl ester (9CI)

Chemical Property:

• PSA: 55.40000
• LogP: 2.12710

Purity/Quality:

98% ^*data from raw suppliers

tert-Butyl(3-methyl-2-oxobutyl)carbamate 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Carbamic acid, (3-methyl-2-oxobutyl)-, 1,1-dimethylethyl ester (9CI)

There total 5 articles about Carbamic acid, (3-methyl-2-oxobutyl)-, 1,1-dimethylethyl ester (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

di-tert-butyl dicarbonate (24424-99-5) + 1-amino-3-methyl-2-butanone monohydrochloride (21419-25-0) → tert-butyl (3-methyl-2-oxobutyl)carbamate (388113-93-7)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 12h;

Reference yield: 79.0%

di-tert-butyl dicarbonate (24424-99-5) + ethyl 5-isopropyl-1,3-oxazole-4-carboxylate (32968-46-0) → tert-butyl (3-methyl-2-oxobutyl)carbamate (388113-93-7)

Guidance literature:

ethyl 5-isopropyl-1,3-oxazole-4-carboxylate; With hydrogenchloride; In water; for 12h; Reflux;

di-tert-butyl dicarbonate; With triethylamine; In dichloromethane; at 20 ℃; for 12h;

Reference yield:

tert-butyl N-{[methoxy(methyl)carbamoyl]methyl}carbamate (121505-93-9) → tert-butyl (3-methyl-2-oxobutyl)carbamate (388113-93-7)

Guidance literature:

With hydrogenchloride; isopropylmagnesium chloride; In tetrahydrofuran; diethyl ether;

upstream raw materials:

tert-butyl N-{[methoxy(methyl)carbamoyl]methyl}carbamate

isopropylmagnesium chloride

di-tert-butyl dicarbonate

1-amino-3-methyl-2-butanone monohydrochloride

Downstream raw materials:

(±)-tert-butyl (2-hydroxy-3-methylbutyl)carbamate