7-Methyl-2-phenylimidazo[1,2-a]pyridine-3-carbaldehyde

Base Information

• Chemical Name: 7-Methyl-2-phenylimidazo[1,2-a]pyridine-3-carbaldehyde
• CAS No.: 300708-60-5
• Molecular Formula: C15H12 N2 O
• Molecular Weight: 236.273
• Hs Code.: 2933990090
• European Community (EC) Number: 673-837-8
• DSSTox Substance ID: DTXSID40374979
• Nikkaji Number: J3.384.832C
• Wikidata: Q82163536
• Mol file: 300708-60-5.mol

Synonyms:300708-60-5;7-methyl-2-phenylimidazo[1,2-a]pyridine-3-carbaldehyde;7-Methyl-2-phenyl-imidazo[1,2-a]pyridine-3-carbaldehyde;5-methyl-2-phenylimidazo[1,2-a]pyridine-3-carbaldehyde;1082395-66-1;DTXSID40374979;BBL022453;MFCD00964682;STK504125;AKOS000266442;AB07825;FS-6241;CS-0361125;FT-0765059;EN300-5550171;A876314;2-Phenyl-7-methylimidazo[1,2-a]pyridine-3-carbaldehyde;Z111566904

Chemical Property of 7-Methyl-2-phenylimidazo[1,2-a]pyridine-3-carbaldehyde

Chemical Property:

• PSA: 34.37000
• LogP: 3.12220
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 236.094963011
• Heavy Atom Count: 18
• Complexity: 301

Purity/Quality:

97% ^*data from raw suppliers

7-Methyl-2-phenylimidazo[1,2-a]pyridine-3-carbaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC2=NC(=C(N2C=C1)C=O)C3=CC=CC=C3

Technology Process of 7-Methyl-2-phenylimidazo[1,2-a]pyridine-3-carbaldehyde

There total 8 articles about 7-Methyl-2-phenylimidazo[1,2-a]pyridine-3-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

N,N,N,N,-tetramethylethylenediamine (110-18-9) + 2-phenyl-7-methylimidazo[1,2-a]pyridine (885-91-6) → 7-methyl-2-phenylimidazo[1,2-a]pyridine-3-carbaldehyde (300708-60-5)

Guidance literature:

With water; rose bengal; potassium iodide; In 1,4-dioxane; at 20 ℃; for 36h; Irradiation;

DOI:10.1039/c8ob00532j

Reference yield: 82.0%

dimethyl sulfoxide (67-68-5,8070-53-9) + 2-phenyl-7-methylimidazo[1,2-a]pyridine (885-91-6) → 7-methyl-2-phenylimidazo[1,2-a]pyridine-3-carbaldehyde (300708-60-5)

Guidance literature:

With oxygen; copper diacetate; acetic acid; at 120 ℃; for 24h;

DOI:10.1039/c4cc09134e

Reference yield: 80.0%

N,N-dimethyl-formamide (68-12-2,33513-42-7) + 2-phenyl-7-methylimidazo[1,2-a]pyridine (885-91-6) → 7-methyl-2-phenylimidazo[1,2-a]pyridine-3-carbaldehyde (300708-60-5)

Guidance literature:

With copper(II) nitrate trihydrate; oxygen; at 130 ℃;

upstream raw materials:

2-Amino-4-methylpyridine

4-methyl-N-(1-phenylallyl)-2-aminopyridine

benzaldehyde

N-benzylidene-N-(4-methylpyridin-2-yl)amine

Downstream raw materials:

N-(4-methylpyridin-2-yl)benzamide