3-chloro-1-(2,3-dichlorophenyl)-4-(4-morpholinyl)-1H-pyrrole-2,5-dione

Base Information

Chemical Name:3-chloro-1-(2,3-dichlorophenyl)-4-(4-morpholinyl)-1H-pyrrole-2,5-dione
CAS No.:307527-74-8
Molecular Formula:C₁₄H₁₁Cl₃N₂O₃
Molecular Weight:361.612
Hs Code.:
Mol file:307527-74-8.mol

Synonyms:3-chloro-1-(2,3-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione

Suppliers and Price of 3-chloro-1-(2,3-dichlorophenyl)-4-(4-morpholinyl)-1H-pyrrole-2,5-dione

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-chloro-1-(2,3-dichlorophenyl)-4-(4-morpholinyl)-1H-pyrrole-2,5-dione

Chemical Property:

Boiling Point:467.2±45.0 °C(Predicted)
PKA:-3.45±0.20(Predicted)
Density:1.61±0.1 g/cm3(Predicted)

Purity/Quality:

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Technology Process of 3-chloro-1-(2,3-dichlorophenyl)-4-(4-morpholinyl)-1H-pyrrole-2,5-dione

There total 3 articles about 3-chloro-1-(2,3-dichlorophenyl)-4-(4-morpholinyl)-1H-pyrrole-2,5-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 110-91-8,99108-56-2
morpholine

: 3,4-dichloro-1-(2,3-dichlorophenyl)-1H-pyrrole-2,5-dione

: 307527-74-8
3-chloro-1-(2,3-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione

Guidance literature:: In dichloromethane; at 20 ℃; for 2h;
DOI:10.1021/jm301565b

Reference yield:

: 608-27-5
2,3-dichloroaniline

: 307527-74-8
3-chloro-1-(2,3-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione

Guidance literature:: Multi-step reaction with 4 steps

1: diethyl ether / 2 h / 20 °C

2: sodium acetate / acetic anhydride / 0.5 h / 20 - 100 °C

3: thionyl chloride; pyridine / 1.25 h / 0 °C / Reflux

4: dichloromethane / 2 h / 20 °C

With pyridine; thionyl chloride; sodium acetate; In diethyl ether; dichloromethane; acetic anhydride;
DOI:10.1021/jm301565b

Reference yield:

: 37010-53-0
1-(2,3-dichlorophenyl)-1H-pyrrole-2,5-dione

: 307527-74-8
3-chloro-1-(2,3-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride; pyridine / 1.25 h / 0 °C / Reflux

2: dichloromethane / 2 h / 20 °C

With pyridine; thionyl chloride; In dichloromethane;
DOI:10.1021/jm301565b