methyl 4-O-acetyl-3-O-[3,6-di-O-benzyl-2-O-(2-dibromomethyl)benzoyl-4-O-methyl-α-D-mannopyranosyl]-2-O-methyl-α-L-fucopyranoside

Base Information

Chemical Name:methyl 4-O-acetyl-3-O-[3,6-di-O-benzyl-2-O-(2-dibromomethyl)benzoyl-4-O-methyl-α-D-mannopyranosyl]-2-O-methyl-α-L-fucopyranoside
CAS No.:176167-76-3
Molecular Formula:C₃₉H₄₆Br₂O₁₂
Molecular Weight:866.595
Hs Code.:

Synonyms:methyl 4-O-acetyl-3-O-[3,6-di-O-benzyl-2-O-(2-dibromomethyl)benzoyl-4-O-methyl-α-D-mannopyranosyl]-2-O-methyl-α-L-fucopyranoside

Suppliers and Price of methyl 4-O-acetyl-3-O-[3,6-di-O-benzyl-2-O-(2-dibromomethyl)benzoyl-4-O-methyl-α-D-mannopyranosyl]-2-O-methyl-α-L-fucopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 4-O-acetyl-3-O-[3,6-di-O-benzyl-2-O-(2-dibromomethyl)benzoyl-4-O-methyl-α-D-mannopyranosyl]-2-O-methyl-α-L-fucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 4-O-acetyl-3-O-[3,6-di-O-benzyl-2-O-(2-dibromomethyl)benzoyl-4-O-methyl-α-D-mannopyranosyl]-2-O-methyl-α-L-fucopyranoside

There total 12 articles about methyl 4-O-acetyl-3-O-[3,6-di-O-benzyl-2-O-(2-dibromomethyl)benzoyl-4-O-methyl-α-D-mannopyranosyl]-2-O-methyl-α-L-fucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 176167-70-7
ethyl 3,6-di-O-benzyl-2-O-(2-dibromomethyl)benzoyl-4-O-methyl-1-thio-α-D-mannopyranoside

: 176039-85-3
methyl 4-O-acetyl-2-O-methyl-α-L-fucopyranoside

: 176167-76-3
methyl 4-O-acetyl-3-O-[3,6-di-O-benzyl-2-O-(2-dibromomethyl)benzoyl-4-O-methyl-α-D-mannopyranosyl]-2-O-methyl-α-L-fucopyranoside

Guidance literature:: With N-iodo-succinimide; trifluorormethanesulfonic acid; 4 A molecular sieve; In diethyl ether; 1,2-dichloro-ethane; at 0 ℃; for 0.25h;
DOI:10.1016/0040-4020(96)00034-8

Reference yield:

: 99603-80-2
methyl 2-O-methyl-α-L-fucose

: 176167-76-3
methyl 4-O-acetyl-3-O-[3,6-di-O-benzyl-2-O-(2-dibromomethyl)benzoyl-4-O-methyl-α-D-mannopyranosyl]-2-O-methyl-α-L-fucopyranoside

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) camphorsulfonic acid, 2.) acetic acid / 1.) acetonitrile, RT, 45 min, 2.) acetonitrile, water, RT, 15 min

2: 94 percent / NIS, TfOH, molecular sieves 4 Angstroem / 1,2-dichloro-ethane; diethyl ether / 0.25 h / 0 °C

With N-iodo-succinimide; trifluorormethanesulfonic acid; 4 A molecular sieve; camphor-10-sulfonic acid; acetic acid; In diethyl ether; 1,2-dichloro-ethane;
DOI:10.1016/0040-4020(96)00034-8

Reference yield:

: 73407-51-9
o-di-bromomethyl-benzoyl chloride

: 176167-76-3
methyl 4-O-acetyl-3-O-[3,6-di-O-benzyl-2-O-(2-dibromomethyl)benzoyl-4-O-methyl-α-D-mannopyranosyl]-2-O-methyl-α-L-fucopyranoside

Guidance literature:: Multi-step reaction with 2 steps

1: 575 mg / pyridine / 4 h / Ambient temperature

2: 94 percent / NIS, TfOH, molecular sieves 4 Angstroem / 1,2-dichloro-ethane; diethyl ether / 0.25 h / 0 °C

With pyridine; N-iodo-succinimide; trifluorormethanesulfonic acid; 4 A molecular sieve; In diethyl ether; 1,2-dichloro-ethane;
DOI:10.1016/0040-4020(96)00034-8