Technology Process of (S)-2-N-(3-O-(propan-2-ol)-1-propyl-4-hydroxybenzene)-3-phenylpropylamide
There total 4 articles about (S)-2-N-(3-O-(propan-2-ol)-1-propyl-4-hydroxybenzene)-3-phenylpropylamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
palladium 10% on activated carbon; hydrogen; toluene-4-sulfonic acid;
In
methanol;
at 60 ℃;
for 2h;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: benzotriazol-1-ol; sodium hydrogencarbonate; dicyclohexyl-carbodiimide / 20 °C
2: potassium carbonate; potassium iodide / acetone / 27 h / 50 °C / Reflux
3: potassium tert-butylate / tetrahydrofuran; dimethyl sulfoxide / 20 - 45 °C
4: toluene-4-sulfonic acid; hydrogen; palladium 10% on activated carbon / methanol / 2 h / 60 °C
With
palladium 10% on activated carbon; potassium tert-butylate; hydrogen; sodium hydrogencarbonate; potassium carbonate; benzotriazol-1-ol; toluene-4-sulfonic acid; dicyclohexyl-carbodiimide; potassium iodide;
In
tetrahydrofuran; methanol; dimethyl sulfoxide; acetone;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: potassium carbonate; potassium iodide / acetone / 27 h / 50 °C / Reflux
2: potassium tert-butylate / tetrahydrofuran; dimethyl sulfoxide / 20 - 45 °C
3: toluene-4-sulfonic acid; hydrogen; palladium 10% on activated carbon / methanol / 2 h / 60 °C
With
palladium 10% on activated carbon; potassium tert-butylate; hydrogen; potassium carbonate; toluene-4-sulfonic acid; potassium iodide;
In
tetrahydrofuran; methanol; dimethyl sulfoxide; acetone;
