CID 10937020

Base Information

Chemical Name:CID 10937020
CAS No.:31337-78-7
Molecular Formula:C₁₄H₁₉FO₉
Molecular Weight:350.298
Hs Code.:2932999099
DSSTox Substance ID:DTXSID00449011
Mol file:31337-78-7.mol

Synonyms:31337-78-7;SCHEMBL7643887;DTXSID00449011;[(2S,3S,4S,5R)-4,5,6-triacetyloxy-2-(fluoromethyl)oxan-3-yl] acetate

Suppliers and Price of CID 10937020

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
TETRA-O-ACETYL-6-DEOXY-6-FLUORO-D-GLUCOPYRANOSE 95.00%
5MG
$ 502.12

Total 2 raw suppliers

Chemical Property of CID 10937020

Chemical Property:

Boiling Point:387.8±42.0 °C(Predicted)
PSA：114.43000
Density:1.30±0.1 g/cm3(Predicted)
LogP:0.03900
XLogP3:1.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:9
Exact Mass:350.10131034
Heavy Atom Count:24
Complexity:507

Purity/Quality:

97% ^*data from raw suppliers

TETRA-O-ACETYL-6-DEOXY-6-FLUORO-D-GLUCOPYRANOSE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)OC1C(OC(C(C1OC(=O)C)OC(=O)C)OC(=O)C)CF
Isomeric SMILES:CC(=O)O[C@@H]1[C@H](OC([C@@H]([C@H]1OC(=O)C)OC(=O)C)OC(=O)C)CF

Technology Process of CID 10937020

There total 1 articles about CID 10937020 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 108-24-7
acetic anhydride

: 4577-39-3
methyl 6-deoxy-6-fluoro-α-D-glucopyranoside

: 31337-78-7,674782-58-2
1,2,3,4-Tetra-O-acetyl-6-deoxy-6-fluoro-D-glucofuranose

Guidance literature:: With sulfuric acid; at 0 ℃;
DOI:10.1021/jo035290r

Reference yield:

: 31337-78-7,674782-58-2
1,2,3,4-Tetra-O-acetyl-6-deoxy-6-fluoro-D-glucofuranose

: 5-O-(6-deoxy-6-fluoro-β-D-glucopyranosyl)neamine tetra(acetic acid) salt

Guidance literature:: Multi-step reaction with 5 steps

1.1: hydrazine acetate / dimethylformamide / 20 °C

2.1: DBU / CH₂Cl₂ / 20 °C

3.1: 22 percent / BF₃*OEt₂ / CH₂Cl₂ / -50 °C

4.1: K₂CO₃ / methanol / 5 h / 20 °C

4.2: aq. NaOH; PMe₃ / tetrahydrofuran / 2 h / 50 °C

5.1: H₂ / Pd(OH)2/C / H₂O / 1 h / 20 °C

With boron trifluoride diethyl etherate; hydrogen; hydrazinium monoacetate; potassium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; palladium dihydroxide; In methanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1021/jo035290r

Reference yield:

: 31337-78-7,674782-58-2
1,2,3,4-Tetra-O-acetyl-6-deoxy-6-fluoro-D-glucofuranose

: (2R,3R,4S,5S,6S)-2-[(1R,2R,3S,5R,6S)-3,5-Diamino-2-((2R,3R,4R,5R,6R)-3-amino-6-aminomethyl-4,5-bis-benzyloxy-tetrahydro-pyran-2-yloxy)-6-benzyloxy-cyclohexyloxy]-6-fluoromethyl-tetrahydro-pyran-3,4,5-triol

Guidance literature:: Multi-step reaction with 4 steps

1.1: hydrazine acetate / dimethylformamide / 20 °C

2.1: DBU / CH₂Cl₂ / 20 °C

3.1: 22 percent / BF₃*OEt₂ / CH₂Cl₂ / -50 °C

4.1: K₂CO₃ / methanol / 5 h / 20 °C

4.2: aq. NaOH; PMe₃ / tetrahydrofuran / 2 h / 50 °C

With boron trifluoride diethyl etherate; hydrazinium monoacetate; potassium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; In methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jo035290r