(S)-4-HEPTANOLIDE STANDARD FOR GC

Base Information

• Chemical Name: (S)-4-HEPTANOLIDE STANDARD FOR GC
• CAS No.: 31323-51-0
• Molecular Formula: C7H12 O2
• Molecular Weight: 128.171
• Hs Code.: 2932209090
• Mol file: 31323-51-0.mol

Synonyms:2(3H)-Furanone,dihydro-5-propyl-, (S)-; 2(3H)-Furanone, dihydro-5-propyl-, (S)-(-)- (8CI);(-)-g-Heptalactone; (S)-4-n-Propylbutyrolactone;(S)-g-Heptalactone; S-(-)-g-Heptalactone

Chemical Property of (S)-4-HEPTANOLIDE STANDARD FOR GC

Chemical Property:

• Vapor Pressure: 0.0827mmHg at 25°C
• Refractive Index: 1.436
• Boiling Point: 226.3°Cat760mmHg
• Flash Point: 85.2°C
• PSA: 26.30000
• Density: 0.983g/cm³
• LogP: 1.49210
• Storage Temp.: −20°C

Purity/Quality:

99% ^*data from raw suppliers

(S)-4-HEPTANOLIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 38
• Safety Statements: 36

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (S)-4-HEPTANOLIDE STANDARD FOR GC

There total 25 articles about (S)-4-HEPTANOLIDE STANDARD FOR GC which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

5-allyl-dihydrofuran-2-one (152723-40-5) → (S)-γ-Propyl-γ-butyrolactone (31323-51-0)

Guidance literature:

With hydrogen; Ra-Ni; In water; ethyl acetate;

DOI:10.1016/S0957-4166(98)00477-7

Reference yield:

(2R,3R)-2,3-epoxy-1-hexanol (92418-71-8) → (S)-γ-Propyl-γ-butyrolactone (31323-51-0)

Guidance literature:

Multi-step reaction with 6 steps

1: 1.) sodium metaperiodate, ruthenium trichloride * 3H₂O / 1.) carbon tetrachloride, acetonitrile, water, room temperature, 1.5 h; 2.) ether, 3 h

3: 6 h / Irradiation

4: 4-(dimethylamino)pyridine / pyridine / 18 h / Ambient temperature

5: hydrogen / Pd

6: 1.) KOH; 2.) p-toluenesulfonic acid / 1.) EtOH, reflux, 15 min; 2.) benzene,

With dmap; ruthenium trichloride; potassium hydroxide; sodium periodate; hydrogen; toluene-4-sulfonic acid; palladium; In pyridine;

Reference yield:

4-propylbutanolide (105-21-5) → (S)-γ-Propyl-γ-butyrolactone (31323-51-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 10percent CaCl₂ / pig pancreatic lipase (PPL) / H₂O / pH=7.2

2: HCl

With hydrogenchloride; calcium chloride; pig pancreatic lipase; In water;

DOI:10.1016/S0040-4039(00)82077-8

upstream raw materials:

(S)-4-Hydroxy-heptanoic acid

Acetic acid (S)-1-phenethyl-butyl ester

(S)-4-Hydroxy-heptanoic acid ethyl ester

5-allyl-dihydrofuran-2-one