N,N-bis[2-(triphenylphosphonio)ethyl]hydroxylamide dibromide

Base Information

• Chemical Name: N,N-bis[2-(triphenylphosphonio)ethyl]hydroxylamide dibromide
• CAS No.: 67456-34-2
• Molecular Formula: 2Br*C₄₀H₃₉NP₂
• Molecular Weight: 755.512
• Mol file: 67456-34-2.mol

Synonyms:N,N-bis[2-(triphenylphosphonio)ethyl]hydroxylamide dibromide

Chemical Property of N,N-bis[2-(triphenylphosphonio)ethyl]hydroxylamide dibromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N-bis[2-(triphenylphosphonio)ethyl]hydroxylamide dibromide

There total 2 articles about N,N-bis[2-(triphenylphosphonio)ethyl]hydroxylamide dibromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

bis(2-bromoethyl)amine (3890-99-1) + triphenylphosphine (603-35-0) → N,N-bis[2-(triphenylphosphonio)ethyl]hydroxylamide dibromide (67456-34-2)

Guidance literature:

In acetonitrile; for 48h; Reflux;

DOI:10.1021/tx500032e

Reference yield:

→ N,N-bis[2-(triphenylphosphonio)ethyl]hydroxylamide dibromide (67456-34-2)

Guidance literature:

Gemisch v. Triphenylphosphin(7) u. Bis-(2-hydroxy-aethyl)-methyl-amin in Bzl., 1.) HBr, 2.) 155grad;

DOI:10.1002/hlca.19780610519

Reference yield: 50.0%

(4R*,5R*)-5-diisopropyloxyphosphoryl-5-methyl-4-(succinimidyloxycarbonyloxymethyl)-1-pyrroline N-oxide + N,N-bis[2-(triphenylphosphonio)ethyl]hydroxylamide dibromide (67456-34-2) → (4R*,5R*)-5-(diisopropyloxyphosphoryl)-5-methyl-4-[({bis[2-(triphenylphosphonio)ethyl]carbamoyl}oxy)methyl]pyrroline N-oxide bromide

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 3h; Inert atmosphere;

DOI:10.1021/tx500032e

upstream raw materials:

bis(2-bromoethyl)amine

triphenylphosphine

Downstream raw materials:

vinyldiphenylphosphine oxide