2-BROMO-N-HYDROXYBENZENECARBOXYMIDOYL CHLORIDE

Base Information

• Chemical Name: 2-BROMO-N-HYDROXYBENZENECARBOXYMIDOYL CHLORIDE
• CAS No.: 38435-47-1
• Molecular Formula: C7H5 Br Cl N O
• Molecular Weight: 234.48
• Hs Code.: 2925290090
• Mol file: 38435-47-1.mol

Synonyms:2-Bromo-N-hydroxybenzenecarboximidoylchloride; 2-Bromobenzohydroximinoyl chloride; N-[(2-Bromophenyl)(chloro)methylene]hydroxyamine

Chemical Property of 2-BROMO-N-HYDROXYBENZENECARBOXYMIDOYL CHLORIDE

Chemical Property:

• PSA: 32.59000
• LogP: 2.82370

Purity/Quality:

2-BROMO-ALPHA-CHLOROBENZALDOXIME 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-BROMO-N-HYDROXYBENZENECARBOXYMIDOYL CHLORIDE

There total 2 articles about 2-BROMO-N-HYDROXYBENZENECARBOXYMIDOYL CHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.3%

2-bromobenzaldehyde oxime (34158-72-0,52707-51-4,52707-56-9) → 2-bromo N-hydroxybenzimidoyl chloride (38435-47-1)

Guidance literature:

With N-chloro-succinimide; In N,N-dimethyl-formamide; at 35 ℃; for 3h;

Reference yield:

ortho-bromobenzaldehyde (6630-33-7) → 2-bromo N-hydroxybenzimidoyl chloride (38435-47-1)

Guidance literature:

Multi-step reaction with 2 steps

1: hydroxylamine hydrochloride; sodium acetate / ethanol

2: N-chloro-succinimide / N,N-dimethyl-formamide / 4 h / 20 °C / Inert atmosphere

With N-chloro-succinimide; hydroxylamine hydrochloride; sodium acetate; In ethanol; N,N-dimethyl-formamide;

DOI:10.1039/c3ob41393d

Reference yield: 98.0%

benzothiophene-1,1-dioxide (825-44-5) + 2-bromo N-hydroxybenzimidoyl chloride (38435-47-1) → C15H10BrNO3S

Guidance literature:

With 1,4-diaza-bicyclo[2.2.2]octane; In ethyl acetate; at 20 ℃; for 1h;

DOI:10.1016/j.tetlet.2020.151943

upstream raw materials:

2-bromobenzaldehyde oxime

ortho-bromobenzaldehyde

Downstream raw materials:

3-(2-bromo-phenyl)-5-methyl-isoxazole-4-carboxylic acid methyl ester

1-bromo-2-isothiocyanatobenzene

3-(o-bromophenyl)-5-(carbamido)imino-Δ²-1,4,2-oxathiazoline

3-(2-bromophenyl)-6-oxo-8,8-dimethyl-1-oxa-2,7-diazaspiro<4.4>non-2-ene