1-[(E)-1-(4-Bromo-phenyl)-3-dimethylamino-prop-2-en-(E)-ylideneamino]-4,6-diphenyl-1H-pyridin-2-one

Base Information

• Chemical Name: 1-[(E)-1-(4-Bromo-phenyl)-3-dimethylamino-prop-2-en-(E)-ylideneamino]-4,6-diphenyl-1H-pyridin-2-one
• CAS No.: 91869-64-6
• Molecular Formula: C₂₈H₂₄BrN₃O
• Molecular Weight: 498.422
• Mol file: 91869-64-6.mol

Synonyms:1-[(E)-1-(4-Bromo-phenyl)-3-dimethylamino-prop-2-en-(E)-ylideneamino]-4,6-diphenyl-1H-pyridin-2-one

Chemical Property of 1-[(E)-1-(4-Bromo-phenyl)-3-dimethylamino-prop-2-en-(E)-ylideneamino]-4,6-diphenyl-1H-pyridin-2-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-[(E)-1-(4-Bromo-phenyl)-3-dimethylamino-prop-2-en-(E)-ylideneamino]-4,6-diphenyl-1H-pyridin-2-one

There total 19 articles about 1-[(E)-1-(4-Bromo-phenyl)-3-dimethylamino-prop-2-en-(E)-ylideneamino]-4,6-diphenyl-1H-pyridin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

N-(α-methyl-4-bromobenzylidenamino)-4,6-diphenyl-2-pyridone (91869-67-9) + N,N-dimethyl-formamide dimethyl acetal (4637-24-5) → 1-[(E)-1-(4-Bromo-phenyl)-3-dimethylamino-prop-2-en-(E)-ylideneamino]-4,6-diphenyl-1H-pyridin-2-one (91869-64-6)

Guidance literature:

In N,N-dimethyl-formamide; for 8h; Heating;

Reference yield:

1-[(E)-1-(4-Chloro-phenyl)-3-dimethylamino-prop-2-en-(E)-ylideneamino]-4,6-diphenyl-1H-pyridin-2-one (91869-63-5) → 1-[(E)-1-(4-Bromo-phenyl)-3-dimethylamino-prop-2-en-(E)-ylideneamino]-4,6-diphenyl-1H-pyridin-2-one (91869-64-6)

Guidance literature:

Multi-step reaction with 4 steps

1: 93 percent / NH₂OH*HCl, CH₃ONa / methanol / 5 h / Heating

2: hydrochloric acid / methanol / 1 h / Heating

3: boron trifluoride etherate / 1.) THF, reflux, 4 h; 2.) DMF, reflux, 5 h.

4: 98 percent / dimethylformamide / 8 h / Heating

With hydrogenchloride; boron trifluoride diethyl etherate; hydroxylamine hydrochloride; sodium methylate; In methanol; N,N-dimethyl-formamide;

Reference yield:

1-[(E)-3-Dimethylamino-1-(4-methoxy-phenyl)-prop-2-en-(E)-ylideneamino]-4,6-diphenyl-1H-pyridin-2-one (91869-62-4) → 1-[(E)-1-(4-Bromo-phenyl)-3-dimethylamino-prop-2-en-(E)-ylideneamino]-4,6-diphenyl-1H-pyridin-2-one (91869-64-6)

Guidance literature:

Multi-step reaction with 4 steps

1: NH₂OH*HCl, CH₃ONa / methanol / 5 h / Heating

2: hydrochloric acid / methanol / 1 h / Heating

3: boron trifluoride etherate / 1.) THF, reflux, 4 h; 2.) DMF, reflux, 5 h.

4: 98 percent / dimethylformamide / 8 h / Heating

With hydrogenchloride; boron trifluoride diethyl etherate; hydroxylamine hydrochloride; sodium methylate; In methanol; N,N-dimethyl-formamide;

upstream raw materials:

N-(α-methyl-4-bromobenzylidenamino)-4,6-diphenyl-2-pyridone

N,N-dimethyl-formamide dimethyl acetal

1-amino-2-oxo-4,6-diphenylpyridine

para-bromoacetophenone

Downstream raw materials:

3-(4-Bromo-phenyl)-3-[(E)-2-oxo-4,6-diphenyl-2H-pyridin-1-ylimino]-propionaldehyde oxime

1-[1-(4-Bromo-phenyl)-3-(phenyl-hydrazono)-prop-(E)-ylideneamino]-4,6-diphenyl-1H-pyridin-2-one

5-(4-Bromophenyl)isoxazole

1-amino-2-oxo-4,6-diphenylpyridine