N-[furan-2-yl(phenyl)methylidene]hydroxylamine

Base Information

• Chemical Name: N-[furan-2-yl(phenyl)methylidene]hydroxylamine
• CAS No.: 91137-23-4
• Molecular Formula: C₁₁H₉NO₂
• Molecular Weight: 187.198
• European Community (EC) Number: 659-997-1
• Nikkaji Number: J738.555B
• Mol file: 91137-23-4.mol

Synonyms:N-[furan-2-yl(phenyl)methylidene]hydroxylamine;2067-52-9;(NE)-N-[furan-2-yl(phenyl)methylidene]hydroxylamine;2-BENZOYLFURAN OXIME;Phenyl(2-furanyl) ketone oxime;AKOS024324670;(E)-furan-2-yl(phenyl)methanone oxime;EN300-101386;N-[(furan-2-yl)(phenyl)methylidene]hydroxylamine

Chemical Property of N-[furan-2-yl(phenyl)methylidene]hydroxylamine

Chemical Property:

• XLogP3: 2.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 187.063328530
• Heavy Atom Count: 14
• Complexity: 209

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=NO)C2=CC=CO2
• Isomeric SMILES: C1=CC=C(C=C1)/C(=N\O)/C2=CC=CO2

Technology Process of N-[furan-2-yl(phenyl)methylidene]hydroxylamine

There total 1 articles about N-[furan-2-yl(phenyl)methylidene]hydroxylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

(furan-2-yl)(phenyl)methanone (2689-59-0) → furan-2-yl-phenyl-methanone oxime (91137-23-4)

Guidance literature:

With pyridine; hydroxylamine hydrochloride; In methanol; for 12h; Heating;

DOI:10.1021/ol070561w

Reference yield: 88.0%

furan-2-yl-phenyl-methanone oxime (91137-23-4) → (furan-2-yl)(phenyl)methanone (2689-59-0)

Guidance literature:

With periodic acid; at 20 ℃; for 0.233333h;

DOI:10.1080/00397910500212833

Reference yield:

furan-2-yl-phenyl-methanone oxime (91137-23-4) → C17H13NO2

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N / CH₂Cl₂ / 0.5 h / 0 °C

2: air / Cu(OAc)2 / dimethylformamide / 2 h / 50 °C

With air; triethylamine; copper diacetate; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/ol070561w

upstream raw materials:

(furan-2-yl)(phenyl)methanone

Downstream raw materials:

(furan-2-yl)(phenyl)methanone

C₁₈H₈F₅NO₃

C₁₈H₈F₅NO₃