2-(1H-pyrazol-3-yl)-1H-benzimidazole

Base Information

Chemical Name:2-(1H-pyrazol-3-yl)-1H-benzimidazole
CAS No.:380653-63-4
Molecular Formula:C10H8 N4
Molecular Weight:184.2
Hs Code.:
UNII:C26MF22L5F
Wikidata:Q27097297
Metabolomics Workbench ID:151214
ChEMBL ID:CHEMBL495758
Mol file:380653-63-4.mol

Synonyms:2-(1H-pyrazol-3-yl)-1H-benzimidazole;380653-63-4;2-(1H-pyrazol-5-yl)-1H-benzimidazole;2-(1H-pyrazol-3-yl)-1H-benzo[d]imidazole;C26MF22L5F;2-(1H-pyrazol-3-yl)-1H-1,3-benzodiazole;1H-Benzimidazole, 2-(1H-pyrazol-3-yl)-;2-(1H-Pyrazol-3-yl)-1H-benzo(d)imidazole;2-(1H-Pyrazol-5-yl)-1H-1,3-benzodiazole;pyrazolylbenzimidazole;2w1d;pyrazole-benzimidazole, 16;JMC52379 Compound 5;UNII-C26MF22L5F;SCHEMBL546102;CHEMBL495758;BDBM24637;IYTGPPNUOLLGBE-UHFFFAOYSA-N;AKOS012380685;DB08065;2-(1H-pyrazol-3yl)-1H-benzoimidazole;PD004821;FT-0757275;Q27097297;L0D

Suppliers and Price of 2-(1H-pyrazol-3-yl)-1H-benzimidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-(1H-PYRAZOL-3-YL)-1H-BENZIMIDAZOLE 95.00%
5MG
$ 498.65

Total 1 raw suppliers

Chemical Property of 2-(1H-pyrazol-3-yl)-1H-benzimidazole

Chemical Property:

PSA：57.36000
LogP:1.95300
XLogP3:1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:184.074896272
Heavy Atom Count:14
Complexity:208

Purity/Quality:: 2-(1H-PYRAZOL-3-YL)-1H-BENZIMIDAZOLE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)NC(=N2)C3=CC=NN3

Technology Process of 2-(1H-pyrazol-3-yl)-1H-benzimidazole

There total 3 articles about 2-(1H-pyrazol-3-yl)-1H-benzimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 1333247-00-9
1-(1H-benzo[d]imidazole-2-yl)-3-(dimethylamino)prop-2-en-1-one

: 380653-63-4
2-(1H-pyrazol-3-yl)-1H-benzoimidazole

Guidance literature:: With hydrazine hydrate; In methanol; for 1h; Reflux;

Reference yield: 69.0%

: 1621-91-6,797027-83-9
1H-pyrazole-3-carboxylic acid

: 95-54-5
1,2-diamino-benzene

: 380653-63-4
2-(1H-pyrazol-3-yl)-1H-benzoimidazole

Guidance literature:: 1H-pyrazole-3-carboxylic acid; 1,2-diamino-benzene; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 24h;

With acetic acid; at 100 ℃; for 4h;
DOI:10.1021/jm800382h

Reference yield:

: 939-70-8
2-acetylbenzimidazole

: 380653-63-4
2-(1H-pyrazol-3-yl)-1H-benzoimidazole

Guidance literature:: Multi-step reaction with 2 steps

1: 1 h / 105 °C

2: hydrazine hydrate / methanol / 1 h / Reflux

With hydrazine hydrate; In methanol;