ethyl (1S,2R,3S)-2-(tert-butoxycarbonylamino)-3-hydroxycyclohexanecarboxylate

Base Information

Chemical Name:ethyl (1S,2R,3S)-2-(tert-butoxycarbonylamino)-3-hydroxycyclohexanecarboxylate
CAS No.:1337970-94-1
Molecular Formula:C₁₄H₂₅NO₅
Molecular Weight:287.356
Hs Code.:

Synonyms:ethyl (1S,2R,3S)-2-(tert-butoxycarbonylamino)-3-hydroxycyclohexanecarboxylate

Suppliers and Price of ethyl (1S,2R,3S)-2-(tert-butoxycarbonylamino)-3-hydroxycyclohexanecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl (1S,2R,3S)-2-(tert-butoxycarbonylamino)-3-hydroxycyclohexanecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl (1S,2R,3S)-2-(tert-butoxycarbonylamino)-3-hydroxycyclohexanecarboxylate

There total 6 articles about ethyl (1S,2R,3S)-2-(tert-butoxycarbonylamino)-3-hydroxycyclohexanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 1337970-90-7
ethyl (1S,2R,3S)-2-(tert-butoxycarbonylamino)-3-hydroxycyclohex-4-enecarboxylate

: 1337970-94-1
ethyl (1S,2R,3S)-2-(tert-butoxycarbonylamino)-3-hydroxycyclohexanecarboxylate

Guidance literature:: With palladium 10% on activated carbon; ammonium acetate; In ethanol; at 75 ℃; for 2h;
DOI:10.1039/c1ob05648d

Reference yield:

: 870288-16-7,233600-33-4
(1R,2S)-2-(tert-butoxycarbonylamino)cyclohex-3-enecarboxylic acid

: 1337970-94-1
ethyl (1S,2R,3S)-2-(tert-butoxycarbonylamino)-3-hydroxycyclohexanecarboxylate

Guidance literature:: Multi-step reaction with 4 steps

1: iodine; sodium hydrogencarbonate; potassium iodide / dichloromethane; water / 16 h / 20 °C

2: 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / 6 h / 65 °C

3: sodium ethanolate / 9 h / 20 °C

4: palladium 10% on activated carbon; ammonium acetate / ethanol / 2 h / 75 °C

With palladium 10% on activated carbon; ammonium acetate; iodine; sodium ethanolate; sodium hydrogencarbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; potassium iodide; In tetrahydrofuran; ethanol; dichloromethane; water;
DOI:10.1039/c1ob05648d

Reference yield:

: tert-butyl (1R,4R,5S,8R)-4-iodo-7-oxo-6-oxabicyclo[3.2.1]octan-8-ylcarbamate

: 1337970-94-1
ethyl (1S,2R,3S)-2-(tert-butoxycarbonylamino)-3-hydroxycyclohexanecarboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / 6 h / 65 °C

2: sodium ethanolate / 9 h / 20 °C

3: palladium 10% on activated carbon; ammonium acetate / ethanol / 2 h / 75 °C

With palladium 10% on activated carbon; ammonium acetate; sodium ethanolate; 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; ethanol;
DOI:10.1039/c1ob05648d