1H-Pyrrole-1-carboxylic acid, 2,5-dihydro-2-(2-oxopropyl)-, methyl ester

Base Information

Chemical Name:1H-Pyrrole-1-carboxylic acid, 2,5-dihydro-2-(2-oxopropyl)-, methyl ester
CAS No.:380367-23-7
Molecular Formula:C₉H₁₃NO₃
Molecular Weight:183.207
Hs Code.:
Mol file:380367-23-7.mol

Synonyms:1H-Pyrrole-1-carboxylic acid, 2,5-dihydro-2-(2-oxopropyl)-, methyl ester

Suppliers and Price of 1H-Pyrrole-1-carboxylic acid, 2,5-dihydro-2-(2-oxopropyl)-, methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of 1H-Pyrrole-1-carboxylic acid, 2,5-dihydro-2-(2-oxopropyl)-, methyl ester

Chemical Property:

PSA：0.00000
LogP:0.00000

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

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Technology Process of 1H-Pyrrole-1-carboxylic acid, 2,5-dihydro-2-(2-oxopropyl)-, methyl ester

There total 2 articles about 1H-Pyrrole-1-carboxylic acid, 2,5-dihydro-2-(2-oxopropyl)-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: (+/-)-methyl (2S,3R)-3-iodo-2-(2-oxopropyl)pyrrolidine-1-carboxylate

: 380367-23-7
-methyl 2-(2-oxopropyl)-2,5-dihydro-1H-pyrrole-1-carboxylate

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; at 20 ℃; for 12h;
DOI:10.1021/jo015877a

Reference yield:

: 74761-41-4,134250-76-3
(S)-1-(methoxycarbonyl)pyrrolidine-2-carboxylic acid

: 380367-23-7
-methyl 2-(2-oxopropyl)-2,5-dihydro-1H-pyrrole-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: PhI(OAc)2; I₂ / acetonitrile / 3 h / 20 °C

1.2: 56 percent / BF₃*Et₂O / acetonitrile / 4 h / 0 - 20 °C

2.1: 99 percent / DBU / CH₂Cl₂ / 12 h / 20 °C

With [bis(acetoxy)iodo]benzene; iodine; 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; acetonitrile;
DOI:10.1021/jo015877a