(R)-4-methyl-2-(4'-trifluoromethyl-5-{1-[1-(4-trifluoromethyl-phenyl)-propyl]-piperidin-3-yl}-biphenyl-3-yl)-pentanoic acid ethyl ester

Base Information

Chemical Name:(R)-4-methyl-2-(4'-trifluoromethyl-5-{1-[1-(4-trifluoromethyl-phenyl)-propyl]-piperidin-3-yl}-biphenyl-3-yl)-pentanoic acid ethyl ester
CAS No.:1145683-22-2
Molecular Formula:C₃₆H₄₁F₆NO₂
Molecular Weight:633.717
Hs Code.:

Synonyms:(R)-4-methyl-2-(4'-trifluoromethyl-5-{1-[1-(4-trifluoromethyl-phenyl)-propyl]-piperidin-3-yl}-biphenyl-3-yl)-pentanoic acid ethyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-4-methyl-2-(4'-trifluoromethyl-5-{1-[1-(4-trifluoromethyl-phenyl)-propyl]-piperidin-3-yl}-biphenyl-3-yl)-pentanoic acid ethyl ester

Chemical Property:

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Technology Process of (R)-4-methyl-2-(4'-trifluoromethyl-5-{1-[1-(4-trifluoromethyl-phenyl)-propyl]-piperidin-3-yl}-biphenyl-3-yl)-pentanoic acid ethyl ester

There total 1 articles about (R)-4-methyl-2-(4'-trifluoromethyl-5-{1-[1-(4-trifluoromethyl-phenyl)-propyl]-piperidin-3-yl}-biphenyl-3-yl)-pentanoic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1145683-21-1
1-(4-(trifluoromethyl)phenyl)propyl methanesulfonate

: 1145683-19-7
4-Methyl-2-(5-piperidin-3-yl-4'-trifluoromethyl-biphenyl-3-yl)-pentanoic acid ethyl ester

: 1145683-23-3
(S)-4-methyl-2-(4'-trifluoromethyl-5-{1-[1-(4-trifluoromethyl-phenyl)-propyl]-piperidin-3-yl}-biphenyl-3-yl)-pentanoic acid ethyl ester

: 1145683-22-2
(R)-4-methyl-2-(4'-trifluoromethyl-5-{1-[1-(4-trifluoromethyl-phenyl)-propyl]-piperidin-3-yl}-biphenyl-3-yl)-pentanoic acid ethyl ester

Guidance literature:: With caesium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 17h;

Reference yield:

: 1145683-22-2
(R)-4-methyl-2-(4'-trifluoromethyl-5-{1-[1-(4-trifluoromethyl-phenyl)-propyl]-piperidin-3-yl}-biphenyl-3-yl)-pentanoic acid ethyl ester

: 1145682-53-6
(R) 4-methyl-2-(4'-trifluoromethyl-5-{1-[1-(4-trifluoromethyl-phenyl)-propyl]-piperidin-3-yl}-biphenyl-3-yl)-pentanoic acid

Guidance literature:: (R)-4-methyl-2-(4'-trifluoromethyl-5-{1-[1-(4-trifluoromethyl-phenyl)-propyl]-piperidin-3-yl}-biphenyl-3-yl)-pentanoic acid ethyl ester; With potassium hydroxide; water; In ethanol; at 78 ℃; for 2h;

With citric acid; In ethanol; dichloromethane; water; pH=~ 7;