trans-10,11-Dibromodibenzosuberone

Base Information

Chemical Name:trans-10,11-Dibromodibenzosuberone
CAS No.:39654-52-9
Molecular Formula:C15H10 Br2 O
Molecular Weight:366.052
Hs Code.:2914700090
European Community (EC) Number:620-606-4
Nikkaji Number:J525.887A
Mol file:39654-52-9.mol

Synonyms:trans-10,11-Dibromodibenzosuberone

Suppliers and Price of trans-10,11-Dibromodibenzosuberone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
10,11-DIBROMO-10,11-DIHYDRO-5H-DIBENZO[A,D]CYCLOHEPTEN-5-ONE 95.00%
5MG
$ 495.29

AHH
trans-10,11-Dibromodibenzosuberone 97%
50g
$ 910.00

Total 5 raw suppliers

Chemical Property of trans-10,11-Dibromodibenzosuberone

Chemical Property:

Vapor Pressure:1.81E-06mmHg at 25°C
Melting Point:213 °C (dec.)(lit.)
Refractive Index:1.677
Boiling Point:395.6°C at 760 mmHg
Flash Point:105.4°C
PSA：17.07000
Density:1.751g/cm³
LogP:4.80320
XLogP3:4.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:365.90779
Heavy Atom Count:18
Complexity:301

Purity/Quality:

97% ^*data from raw suppliers

10,11-DIBROMO-10,11-DIHYDRO-5H-DIBENZO[A,D]CYCLOHEPTEN-5-ONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(C(C3=CC=CC=C3C2=O)Br)Br
Isomeric SMILES:C1=CC=C2C(=C1)[C@H]([C@@H](C3=CC=CC=C3C2=O)Br)Br
Uses 10,11-Dibromo10,11-dihydro-5-dibenzosuberenone is an intermediate in the synthesis of 10-Hydroxy (E)-Amitriptyline (D462790). (5E)-5-[3-(dimethylamino)propylidene]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-10-ol is a metabolite of amitriptyline (A633350) which is a dibenzocycloheptadiene derivative and an antidepressant (1). Amitriptyline is also a TrkA and TrkB receptor agonist and exhibits neurotrophic and anti-inflammatory activities (2,3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA).

Technology Process of trans-10,11-Dibromodibenzosuberone

There total 2 articles about trans-10,11-Dibromodibenzosuberone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%