DL-2,3,4,5-Tetra-O-benzyl-1-deoxy-1-fluoro-6-O-tosyl-scyllo-inositol

Base Information

• Chemical Name: DL-2,3,4,5-Tetra-O-benzyl-1-deoxy-1-fluoro-6-O-tosyl-scyllo-inositol
• CAS No.: 129670-44-6
• Molecular Formula: C₄₁H₄₁FO₇S
• Molecular Weight: 696.837
• Mol file: 129670-44-6.mol

Synonyms:DL-2,3,4,5-Tetra-O-benzyl-1-deoxy-1-fluoro-6-O-tosyl-scyllo-inositol

Chemical Property of DL-2,3,4,5-Tetra-O-benzyl-1-deoxy-1-fluoro-6-O-tosyl-scyllo-inositol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of DL-2,3,4,5-Tetra-O-benzyl-1-deoxy-1-fluoro-6-O-tosyl-scyllo-inositol

There total 7 articles about DL-2,3,4,5-Tetra-O-benzyl-1-deoxy-1-fluoro-6-O-tosyl-scyllo-inositol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

(+/-)-1-O-p-toluenesulfonyl-3,4,5,6-tetra-O-benzyl-myo-inositol (6383-01-3,97371-75-0) → DL-2,3,4,5-Tetra-O-benzyl-1-deoxy-1-fluoro-6-O-tosyl-scyllo-inositol (129670-44-6)

Guidance literature:

With diethylamino-sulfur trifluoride; for 4h; Ambient temperature;

Reference yield:

rac-1,4,5,6-tetra-O-benzyl-myo-inositol (26276-99-3) → DL-2,3,4,5-Tetra-O-benzyl-1-deoxy-1-fluoro-6-O-tosyl-scyllo-inositol (129670-44-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 79 percent / pyridine

2: 75 percent / (diethylamino)sulfur trifluoride / CH₂Cl₂

With pyridine; diethylamino-sulfur trifluoride; In dichloromethane;

DOI:10.1039/p19960001845

Reference yield:

p-toluenesulfonyl chloride (98-59-9) → DL-2,3,4,5-Tetra-O-benzyl-1-deoxy-1-fluoro-6-O-tosyl-scyllo-inositol (129670-44-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 79 percent / pyridine

2: 75 percent / (diethylamino)sulfur trifluoride / CH₂Cl₂

With pyridine; diethylamino-sulfur trifluoride; In dichloromethane;

DOI:10.1039/p19960001845

upstream raw materials:

(+/-)-1-O-p-toluenesulfonyl-3,4,5,6-tetra-O-benzyl-myo-inositol

rac-1,4,5,6-tetra-O-benzyl-myo-inositol

p-toluenesulfonyl chloride

benzyl bromide

Downstream raw materials:

(+)-1L-3,4,5,6-Tetra-O-benzyl-1-deoxy-1-fluoro-myo-inositol

(-)-1D-3,4,5,6-Tetra-O-benzyl-1-deoxy-1-fluoro-myo-inositol

DL-3,4,5,6-Tetra-O-benzyl-1-deoxy-1-fluoro-myo-inositol

(1S,2S,3R,4S,5R,6R)-2,3,4,5-Tetrakis-benzyloxy-6-fluoro-cyclohexanol