5-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl)-2-methylfuran-3-carbohydrazide

Base Information

Chemical Name:5-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl)-2-methylfuran-3-carbohydrazide
CAS No.:1465001-40-4
Molecular Formula:C₁₄H₁₁ClN₄O₃
Molecular Weight:318.719
Hs Code.:

Synonyms:5-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl)-2-methylfuran-3-carbohydrazide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl)-2-methylfuran-3-carbohydrazide

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Technology Process of 5-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl)-2-methylfuran-3-carbohydrazide

There total 4 articles about 5-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl)-2-methylfuran-3-carbohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 1465001-33-5
C₁₆H₁₃ClN₂O₄

: 1465001-40-4
5-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl)-2-methylfuran-3-carbohydrazide

Guidance literature:: With hydrazine hydrate; for 1h; Reflux;
DOI:10.3390/molecules18078550

Reference yield:

: 19615-48-6
5-formyl-2-methyl-furan-3-carboxylic acid ethyl ester

: 1465001-40-4
5-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl)-2-methylfuran-3-carbohydrazide

Guidance literature:: Multi-step reaction with 3 steps

1: ethanol / Reflux

2: chloroamine-T / ethanol / Reflux

3: hydrazine hydrate / 1 h / Reflux

With chloroamine-T; hydrazine hydrate; In ethanol;
DOI:10.3390/molecules18078550

Reference yield:

: ethyl 5-(1,2,3,4-tetrahydroxybutyl)-2-methylfuran-3-carboxylate

: 1465001-40-4
5-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl)-2-methylfuran-3-carbohydrazide

Guidance literature:: Multi-step reaction with 4 steps

1: sodium periodate

2: ethanol / Reflux

3: chloroamine-T / ethanol / Reflux

4: hydrazine hydrate / 1 h / Reflux

With sodium periodate; chloroamine-T; hydrazine hydrate; In ethanol;
DOI:10.3390/molecules18078550