C₂₁H₁₈N₄O₂

Base Information

Chemical Name:C₂₁H₁₈N₄O₂
CAS No.:1426935-47-8
Molecular Formula:C₂₁H₁₈N₄O₂
Molecular Weight:358.4
Hs Code.:

C<sub>21</sub>H<sub>18</sub>N<sub>4</sub>O<sub>2</sub>

Synonyms:C₂₁H₁₈N₄O₂

Suppliers and Price of C₂₁H₁₈N₄O₂

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of C₂₁H₁₈N₄O₂

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of C₂₁H₁₈N₄O₂

There total 5 articles about C₂₁H₁₈N₄O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 1227077-01-1
ethyl 6-oxo-1-(pyridin-4-ylmethyl)-6,7-dihydro-1H-pyrazolo[3,4-b]pyridine-4-carboxylate

: 98-80-6
phenylboronic acid

: 1426935-47-8
C₂₁H₁₈N₄O₂

Guidance literature:: ethyl 6-oxo-1-(pyridin-4-ylmethyl)-6,7-dihydro-1H-pyrazolo[3,4-b]pyridine-4-carboxylate; With triethylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate; In 1,4-dioxane; at 20 ℃; for 2h;

phenylboronic acid; With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In 1,4-dioxane; water; at 100 ℃; for 4h;
DOI:10.1021/jm301709s

Reference yield:

: 872-85-5
pyridine-4-carbaldehyde

: 1426935-47-8
C₂₁H₁₈N₄O₂

Guidance literature:: Multi-step reaction with 5 steps

1.1: hydrazine hydrate / ethanol / 24 h / 0 - 20 °C

1.2: 2 h / 20 °C

2.1: sodium butanolate / butan-1-ol / 120 °C

3.1: benzene / 15 h / 65 °C

4.1: acetic acid / 4 h / Reflux

5.1: bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate; triethylamine / 1,4-dioxane / 2 h / 20 °C

5.2: 4 h / 100 °C

With hydrazine hydrate; acetic acid; triethylamine; sodium butanolate; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate; In 1,4-dioxane; ethanol; butan-1-ol; benzene; 5.2: |Suzuki Coupling;
DOI:10.1021/jm301709s

Reference yield:

: 202344-41-0
1-(pyridin-4-ylmethyl)-1H-pyrazol-5-amine

: 1426935-47-8
C₂₁H₁₈N₄O₂

Guidance literature:: Multi-step reaction with 3 steps

1.1: benzene / 15 h / 65 °C

2.1: acetic acid / 4 h / Reflux

3.1: bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate; triethylamine / 1,4-dioxane / 2 h / 20 °C

3.2: 4 h / 100 °C

With acetic acid; triethylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate; In 1,4-dioxane; benzene; 3.2: |Suzuki Coupling;
DOI:10.1021/jm301709s