2-benzyl-3a-hydroxy-1-oxo-6,6-diphenyl-hexahydro-4,5-dioxa-2-aza-indene-7a-carboxylic acid ethyl ester

Base Information

• Chemical Name: 2-benzyl-3a-hydroxy-1-oxo-6,6-diphenyl-hexahydro-4,5-dioxa-2-aza-indene-7a-carboxylic acid ethyl ester
• CAS No.: 216175-07-4
• Molecular Formula: C₂₈H₂₇NO₆
• Molecular Weight: 473.525
• Mol file: 216175-07-4.mol

Synonyms:2-benzyl-3a-hydroxy-1-oxo-6,6-diphenyl-hexahydro-4,5-dioxa-2-aza-indene-7a-carboxylic acid ethyl ester

Chemical Property of 2-benzyl-3a-hydroxy-1-oxo-6,6-diphenyl-hexahydro-4,5-dioxa-2-aza-indene-7a-carboxylic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-benzyl-3a-hydroxy-1-oxo-6,6-diphenyl-hexahydro-4,5-dioxa-2-aza-indene-7a-carboxylic acid ethyl ester

There total 1 articles about 2-benzyl-3a-hydroxy-1-oxo-6,6-diphenyl-hexahydro-4,5-dioxa-2-aza-indene-7a-carboxylic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

1,1-Diphenylethylene (530-48-3) + ethyl 1-benzyl-4-hydroxy-3-pyrrolin-2-one-3-carboxylate (67513-35-3) → 2-benzyl-3a-hydroxy-1-oxo-6,6-diphenyl-hexahydro-4,5-dioxa-2-aza-indene-7a-carboxylic acid ethyl ester (216175-07-4)

Guidance literature:

With air; manganese triacetate; In acetic acid; at 23 ℃; for 14h;

DOI:10.1016/S0040-4039(98)01765-1

Reference yield: 98.0%

2-benzyl-3a-hydroxy-1-oxo-6,6-diphenyl-hexahydro-4,5-dioxa-2-aza-indene-7a-carboxylic acid ethyl ester (216175-07-4) → cis-7-benzyl-5-ethoxycarbonyl-1-hydroxy-3,3-diphenyl-7-aza-2-oxabicyclo<3.3.0>octan-6-one

Guidance literature:

With hydrogen; palladium on activated charcoal; In dichloromethane; at 40 ℃; for 1h; under 38000 Torr;

DOI:10.1016/S0040-4039(99)00604-8

Reference yield:

2-benzyl-3a-hydroxy-1-oxo-6,6-diphenyl-hexahydro-4,5-dioxa-2-aza-indene-7a-carboxylic acid ethyl ester (216175-07-4) → 3-benzyl-1-ethoxycarbonyl-5-hydroxy-7,7-diphenyl-3-aza-6-oxybicyclo<3.3.0>octan-2-one

Guidance literature:

With hydrogen; palladium on activated charcoal; In dichloromethane; at 40 ℃; for 1h; under 38000 Torr; Yield given;

DOI:10.1016/S0040-4039(98)01765-1

upstream raw materials:

1,1-Diphenylethylene

ethyl 1-benzyl-4-hydroxy-3-pyrrolin-2-one-3-carboxylate