(+)-iso-pestalazine A

Base Information

Chemical Name:(+)-iso-pestalazine A
CAS No.:1082056-99-2
Molecular Formula:C₃₇H₃₈N₆O₄
Molecular Weight:630.747
Hs Code.:

Synonyms:(+)-iso-pestalazine A

Suppliers and Price of (+)-iso-pestalazine A

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (+)-iso-pestalazine A

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (+)-iso-pestalazine A

There total 26 articles about (+)-iso-pestalazine A which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: C₃₇H₃₈N₆O₅

: 1082056-99-2
(+)-iso-pestalazine A

Guidance literature:: With triethylsilane; methanesulfonic acid; In dichloromethane; at 23 ℃; for 4h; Inert atmosphere;
DOI:10.1021/jacs.5b12392

Reference yield:

: 86961-51-5
(S)-benzyl 3-(2-((tert-butoxycarbonyl)amino)-3-methoxy-3-oxopropyl)-1H-indole-1-carboxylate

: 1082056-99-2
(+)-iso-pestalazine A

Guidance literature:: Multi-step reaction with 11 steps

1.1: trifluoroacetic acid / dichloromethane / 2 h / 23 °C / Inert atmosphere

1.2: 2 h / 0 - 23 °C / Molecular sieve; Inert atmosphere

2.1: trifluoroacetic acid / dichloromethane / 1 h / 23 °C / Inert atmosphere

2.2: 18 h / 0 - 23 °C / Inert atmosphere

3.1: boron trifluoride diethyl etherate / acetonitrile / 0.33 h / 0 °C / Inert atmosphere

3.2: 0.83 h / 0 °C / Inert atmosphere

4.1: N-chloro-succinimide; titanium tetrachloride / dichloromethane; acetonitrile / 15 h / 23 °C / Inert atmosphere

5.1: water; silver hexafluoroantimonate / nitromethane / 2 h / 23 °C / Inert atmosphere

6.1: 2,6-dimethylpyridine / dichloromethane / 35 h / 23 °C / Inert atmosphere

7.1: palladium diacetate; triethylsilane; triethylamine / dichloromethane / 3.5 h / 23 °C / Inert atmosphere

8.1: silver hexafluoroantimonate; 2,6-di-tert-butyl-4-methylpyridine / 0.67 h / 23 °C / Inert atmosphere

9.1: palladium 10% on activated carbon; ammonium formate / ethanol / 20 h / 70 °C / Inert atmosphere

10.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 23 °C / Inert atmosphere

11.1: triethylsilane; methanesulfonic acid / dichloromethane / 4 h / 23 °C / Inert atmosphere

With 2,6-dimethylpyridine; triethylsilane; N-chloro-succinimide; silver hexafluoroantimonate; 2,6-di-tert-butyl-4-methylpyridine; methanesulfonic acid; palladium 10% on activated carbon; boron trifluoride diethyl etherate; tetrabutyl ammonium fluoride; water; ammonium formate; palladium diacetate; titanium tetrachloride; triethylamine; trifluoroacetic acid; In tetrahydrofuran; nitromethane; ethanol; dichloromethane; acetonitrile; 8.1: |Friedel-Crafts Alkylation;
DOI:10.1021/jacs.5b12392

Reference yield:

: 16937-99-8,53296-34-7
N-Boc-D-Leu

: 1082056-99-2
(+)-iso-pestalazine A

Guidance literature:: Multi-step reaction with 11 steps

1.1: trifluoroacetic acid / dichloromethane / 2 h / 23 °C / Inert atmosphere

1.2: 2 h / 0 - 23 °C / Molecular sieve; Inert atmosphere

2.1: trifluoroacetic acid / dichloromethane / 1 h / 23 °C / Inert atmosphere

2.2: 18 h / 0 - 23 °C / Inert atmosphere

3.1: boron trifluoride diethyl etherate / acetonitrile / 0.33 h / 0 °C / Inert atmosphere

3.2: 0.83 h / 0 °C / Inert atmosphere

4.1: N-chloro-succinimide; titanium tetrachloride / dichloromethane; acetonitrile / 15 h / 23 °C / Inert atmosphere

5.1: water; silver hexafluoroantimonate / nitromethane / 2 h / 23 °C / Inert atmosphere

6.1: 2,6-dimethylpyridine / dichloromethane / 35 h / 23 °C / Inert atmosphere

7.1: palladium diacetate; triethylsilane; triethylamine / dichloromethane / 3.5 h / 23 °C / Inert atmosphere

8.1: silver hexafluoroantimonate; 2,6-di-tert-butyl-4-methylpyridine / 0.67 h / 23 °C / Inert atmosphere

9.1: palladium 10% on activated carbon; ammonium formate / ethanol / 20 h / 70 °C / Inert atmosphere

10.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 23 °C / Inert atmosphere

11.1: triethylsilane; methanesulfonic acid / dichloromethane / 4 h / 23 °C / Inert atmosphere

With 2,6-dimethylpyridine; triethylsilane; N-chloro-succinimide; silver hexafluoroantimonate; 2,6-di-tert-butyl-4-methylpyridine; methanesulfonic acid; palladium 10% on activated carbon; boron trifluoride diethyl etherate; tetrabutyl ammonium fluoride; water; ammonium formate; palladium diacetate; titanium tetrachloride; triethylamine; trifluoroacetic acid; In tetrahydrofuran; nitromethane; ethanol; dichloromethane; acetonitrile; 8.1: |Friedel-Crafts Alkylation;
DOI:10.1021/jacs.5b12392