rhodamine B-2-hydroxyethyl methacrylate

Base Information

• Chemical Name: rhodamine B-2-hydroxyethyl methacrylate
• CAS No.: 141098-60-4
• Molecular Formula: C₃₄H₃₉N₂O₅*Cl
• Molecular Weight: 591.147
• Mol file: 141098-60-4.mol

Synonyms:rhodamine B-2-hydroxyethyl methacrylate

Chemical Property of rhodamine B-2-hydroxyethyl methacrylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of rhodamine B-2-hydroxyethyl methacrylate

There total 4 articles about rhodamine B-2-hydroxyethyl methacrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

2-methyl-2-propenoic acid 2-hydroxyethyl ester (868-77-9,141668-69-1,25736-86-1,82601-55-6,25249-16-5) + rhodamine B (81-88-9) → rhodamine B-2-hydroxyethyl methacrylate (141098-60-4)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 0 - 20 ℃; for 16.5h;

Reference yield:

N-(9-(2-(chlorocarbonyl)phenyl)-6-(diethylamino)-3H-xanthen-3-ylidene)-N-ethylethanaminium chloride + 2-methyl-2-propenoic acid 2-hydroxyethyl ester (868-77-9,141668-69-1,25736-86-1,82601-55-6,25249-16-5) → rhodamine B-2-hydroxyethyl methacrylate (141098-60-4)

Guidance literature:

With triethylamine; at 5 ℃; for 2h;

Reference yield:

3-diethylaminophenol (91-68-9) → rhodamine B-2-hydroxyethyl methacrylate (141098-60-4)

Guidance literature:

Multi-step reaction with 3 steps

1.1: 1,2-dichloro-benzene / 13 h / 175 °C

1.2: 0.5 h / 25 °C

1.3: 1 h / 80 °C

2.1: thionyl chloride; N,N-dimethyl-formamide / dichloromethane / 2 h / 25 - 40 °C

3.1: triethylamine / 2 h / 5 °C

With thionyl chloride; triethylamine; N,N-dimethyl-formamide; In dichloromethane; 1,2-dichloro-benzene;

upstream raw materials:

2-methyl-2-propenoic acid 2-hydroxyethyl ester

rhodamine B

3-diethylaminophenol

phthalic anhydride

Refernces

• 1、 Besford, Quinn A.,Christofferson, Andrew J.,Fery, Andreas,Merlitz, Holger,Sommer, Jens-Uwe,Uhlmann, Petra,Yong, Huaisong. "FRET-Integrated Polymer Brushes for Spatially Resolved Sensing of Changes in Polymer Conformation". . p. 16600 - 16606. Retrieved 2021.
• 2、 -. "ENGINEERED CELLS AND AGENT COMPOSITIONS FOR THERAPEUTIC AGENT DELIVERY AND TREATMENTS USING SAME". Paragraph 0412-0413. . Retrieved 2020/09/15.
• 3、 -. "RHODAMINE-BASED COLORING COMPOSITION". Paragraph 0308. . Retrieved 2017/06/23.