(E)-3-(Methoxycarbonyl)-4-(5-methylfuran-2-yl)but-3-enoic acid

Base Information

• Chemical Name: (E)-3-(Methoxycarbonyl)-4-(5-methylfuran-2-yl)but-3-enoic acid
• CAS No.: 37978-59-9
• Molecular Formula: C₁₁H₁₂O₅
• Molecular Weight: 224.213
• Hs Code.: 2932190090
• Mol file: 37978-59-9.mol

Synonyms:Butanedioicacid, [(5-methyl-2-furanyl)methylene]-, 1-methyl ester, (2E)- (9CI); Butanedioicacid, [(5-methyl-2-furanyl)methylene]-, 1-methyl ester, (E)-

Chemical Property of (E)-3-(Methoxycarbonyl)-4-(5-methylfuran-2-yl)but-3-enoic acid

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.55
• Boiling Point: 365.43°C at 760 mmHg
• PKA: 3.68±0.10(Predicted)
• Flash Point: 174.806°C
• PSA: 76.74000
• Density: 1.267g/cm³
• LogP: 1.61910
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

(E)-3-(Methoxycarbonyl)-4-(5-methylfuran-2-yl)but-3-enoicacid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (E)-3-(Methoxycarbonyl)-4-(5-methylfuran-2-yl)but-3-enoic acid

There total 2 articles about (E)-3-(Methoxycarbonyl)-4-(5-methylfuran-2-yl)but-3-enoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

E-3-methoxycarbonyl-4-(5-methylfur-2-yl)-but-3-enoic acid t-butyl ester (697748-19-9) → E-3-methoxycarbonyl-4-(5-methylfur-2-yl)-but-3-enoic acid (37978-59-9)

Guidance literature:

With trifluoroacetic acid; In water; at 20 ℃; for 0.333333h;

Reference yield:

→ E-3-methoxycarbonyl-4-(5-methylfur-2-yl)-but-3-enoic acid (37978-59-9)

Guidance literature:

5-Methyl-furan-2-aldehyd, Dimethylsuccinat/t-Butanol/KO-t.Bu;

Reference yield: 92.0%

E-3-methoxycarbonyl-4-(5-methylfur-2-yl)-but-3-enoic acid (37978-59-9) → 4-acetoxy-2-methyl-benzofuran-6-carboxylic acid methyl ester (37978-61-3)

Guidance literature:

With potassium acetate; In acetic anhydride; at 140 ℃; for 0.25h;

upstream raw materials:

E-3-methoxycarbonyl-4-(5-methylfur-2-yl)-but-3-enoic acid t-butyl ester

Downstream raw materials:

4-acetoxy-2-methyl-benzofuran-6-carboxylic acid methyl ester

Refernces