17α-acetoxy-3,3-[1,2-ethanediylbis(oxy)]-5α-hydroxy-11β-[4-(N-piperidino)phenyl]-19-norpregn-9-en-20-one

Base Information

Chemical Name:17α-acetoxy-3,3-[1,2-ethanediylbis(oxy)]-5α-hydroxy-11β-[4-(N-piperidino)phenyl]-19-norpregn-9-en-20-one
CAS No.:240806-34-2
Molecular Formula:C₃₅H₄₇NO₆
Molecular Weight:577.761
Hs Code.:

Synonyms:17α-acetoxy-3,3-[1,2-ethanediylbis(oxy)]-5α-hydroxy-11β-[4-(N-piperidino)phenyl]-19-norpregn-9-en-20-one

Suppliers and Price of 17α-acetoxy-3,3-[1,2-ethanediylbis(oxy)]-5α-hydroxy-11β-[4-(N-piperidino)phenyl]-19-norpregn-9-en-20-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 17α-acetoxy-3,3-[1,2-ethanediylbis(oxy)]-5α-hydroxy-11β-[4-(N-piperidino)phenyl]-19-norpregn-9-en-20-one

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 17α-acetoxy-3,3-[1,2-ethanediylbis(oxy)]-5α-hydroxy-11β-[4-(N-piperidino)phenyl]-19-norpregn-9-en-20-one

There total 3 articles about 17α-acetoxy-3,3-[1,2-ethanediylbis(oxy)]-5α-hydroxy-11β-[4-(N-piperidino)phenyl]-19-norpregn-9-en-20-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 22148-20-5
N-(4-bromophenyl)piperidine

: C₂₄H₃₂O₆

: 240806-34-2
17α-acetoxy-3,3-[1,2-ethanediylbis(oxy)]-5α-hydroxy-11β-[4-(N-piperidino)phenyl]-19-norpregn-9-en-20-one

Guidance literature:: With magnesium; ethylene dibromide; In tetrahydrofuran; at 0 ℃; for 0.25h; Inert atmosphere;

Reference yield: 75.0%

: C₁₁H₁₄BrMgN

: 240806-34-2
17α-acetoxy-3,3-[1,2-ethanediylbis(oxy)]-5α-hydroxy-11β-[4-(N-piperidino)phenyl]-19-norpregn-9-en-20-one

Guidance literature:: 17α-acetoxy-3,3-[1,2-ethanediylbis(oxy)]-5,10α-oxido-19-norpregn-9(11)-en-20-one; With copper(l) iodide; In tetrahydrofuran;

C₁₁H₁₄BrMgN; In tetrahydrofuran; at 0 ℃; for 0.166667h;

Reference yield:

: 240806-31-9
17α-acetoxy-3,3[1,2-ethanediylbis(oxy)]-19-norpregna-5(10),9(11)-diene-20-one

: 240806-34-2
17α-acetoxy-3,3-[1,2-ethanediylbis(oxy)]-5α-hydroxy-11β-[4-(N-piperidino)phenyl]-19-norpregn-9-en-20-one

Guidance literature:: Multi-step reaction with 2 steps

1: disodium hydrogenphosphate; 1,1,1,3,3,3-hexafluoro-2-propanone trihydrate; dihydrogen peroxide / dichloromethane / 12 h / 0 °C

2: magnesium; ethylene dibromide / tetrahydrofuran / 0.25 h / 0 °C / Inert atmosphere

With disodium hydrogenphosphate; 1,1,1,3,3,3-hexafluoro-2-propanone trihydrate; dihydrogen peroxide; magnesium; ethylene dibromide; In tetrahydrofuran; dichloromethane; 2: |Grignard Reaction;