Technology Process of C33H35N5O8
There total 6 articles about C33H35N5O8 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
(S)-N-((4-(2-((tert-butoxycarbonyl)amino)-2-carboxyethyl)phenoxy)carbonyl)-3-phenylsydnonimine; methyl (2S)-2-amino-3-phenylpropanoate hydrochloride;
With
N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate;
In
N,N-dimethyl-formamide;
at 0 ℃;
for 0.25h;
With
N-ethyl-N,N-diisopropylamine;
In
N,N-dimethyl-formamide;
at 0 - 20 ℃;
for 18h;
DOI:10.1039/c3ob41047a
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: isopentyl nitrite / diethyl ether / 16 h / 20 °C / Darkness
1.2: 0.25 h / 20 °C
2.1: triethylamine / dichloromethane / 16 h / -20 - 20 °C
3.1: acetonitrile / 18 h / Reflux
4.1: sodium hydroxide; water / tetrahydrofuran / 20 °C
5.1: N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / N,N-dimethyl-formamide / 0.25 h / 0 °C
5.2: 18 h / 0 - 20 °C
With
water; triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; sodium hydroxide; isopentyl nitrite;
In
tetrahydrofuran; diethyl ether; dichloromethane; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1039/c3ob41047a
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: potassium carbonate; sodium iodide / acetone / 12 h / 20 °C / Darkness
2.1: isopentyl nitrite / diethyl ether / 16 h / 20 °C / Darkness
2.2: 0.25 h / 20 °C
3.1: triethylamine / dichloromethane / 16 h / -20 - 20 °C
4.1: acetonitrile / 18 h / Reflux
5.1: sodium hydroxide; water / tetrahydrofuran / 20 °C
6.1: N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / N,N-dimethyl-formamide / 0.25 h / 0 °C
6.2: 18 h / 0 - 20 °C
With
water; potassium carbonate; triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; sodium iodide; sodium hydroxide; isopentyl nitrite;
In
tetrahydrofuran; diethyl ether; dichloromethane; N,N-dimethyl-formamide; acetone; acetonitrile;
DOI:10.1039/c3ob41047a
