(3,4-Dimethoxy-6-methoxycarbonyl)-benzyliden-malonsaeuredinitril

Base Information

• Chemical Name: (3,4-Dimethoxy-6-methoxycarbonyl)-benzyliden-malonsaeuredinitril
• CAS No.: 136310-43-5
• Molecular Formula: C₁₄H₁₂N₂O₄
• Molecular Weight: 272.26
• Mol file: 136310-43-5.mol

Synonyms:(3,4-Dimethoxy-6-methoxycarbonyl)-benzyliden-malonsaeuredinitril

Chemical Property of (3,4-Dimethoxy-6-methoxycarbonyl)-benzyliden-malonsaeuredinitril

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3,4-Dimethoxy-6-methoxycarbonyl)-benzyliden-malonsaeuredinitril

There total 1 articles about (3,4-Dimethoxy-6-methoxycarbonyl)-benzyliden-malonsaeuredinitril which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

2-formyl-4,5-dimethoxybenzoic acid methyl ester (53012-84-3) + malononitrile (109-77-3) → (3,4-Dimethoxy-6-methoxycarbonyl)-benzyliden-malonsaeuredinitril (136310-43-5)

Guidance literature:

With 3-amino propanoic acid; In ethanol;

DOI:10.1002/ardp.2503240805

Reference yield: 79.0%

(3,4-Dimethoxy-6-methoxycarbonyl)-benzyliden-malonsaeuredinitril (136310-43-5) → (3,4-Dimethoxy-6-methoxycarbonyl)-benzyl-malonsaeuredinitril (136310-45-7)

Guidance literature:

With sodium tetrahydroborate; In methanol; Ambient temperature;

DOI:10.1002/ardp.2503240805

Reference yield:

(3,4-Dimethoxy-6-methoxycarbonyl)-benzyliden-malonsaeuredinitril (136310-43-5) → 4,5-Dimethoxy-2-(2,4,6-triamino-pyrimidin-5-ylmethyl)-benzoic acid methyl ester

Guidance literature:

Multi-step reaction with 2 steps

1: 79 percent / NaBH₄ / methanol / Ambient temperature

2: 1.) Na / 1.) n-butanol 2.) reflux

With sodium tetrahydroborate; sodium; In methanol;

DOI:10.1002/ardp.2503240805

upstream raw materials:

2-formyl-4,5-dimethoxybenzoic acid methyl ester

malononitrile

Downstream raw materials:

(3,4-Dimethoxy-6-methoxycarbonyl)-benzyl-malonsaeuredinitril