N-benzyl-N-(2-p-hydroxyphenoxyethyl)-3-o-fluorophenoxy-2-hydroxypropylamine

Base Information

Chemical Name:N-benzyl-N-(2-p-hydroxyphenoxyethyl)-3-o-fluorophenoxy-2-hydroxypropylamine
CAS No.:107332-67-2
Molecular Formula:C₂₄H₂₆FNO₄
Molecular Weight:411.473
Hs Code.:

Synonyms:N-benzyl-N-(2-p-hydroxyphenoxyethyl)-3-o-fluorophenoxy-2-hydroxypropylamine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-benzyl-N-(2-p-hydroxyphenoxyethyl)-3-o-fluorophenoxy-2-hydroxypropylamine

Chemical Property:

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Technology Process of N-benzyl-N-(2-p-hydroxyphenoxyethyl)-3-o-fluorophenoxy-2-hydroxypropylamine

There total 1 articles about N-benzyl-N-(2-p-hydroxyphenoxyethyl)-3-o-fluorophenoxy-2-hydroxypropylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 15620-80-1
1-(2,3-epoxypropoxy)-2-fluorobenzene

: 107332-63-8
N-benzyl-2-(4-hydroxyphenoxy)ethylamine hydrochloride

: 107332-67-2
N-benzyl-N-(2-p-hydroxyphenoxyethyl)-3-o-fluorophenoxy-2-hydroxypropylamine

Guidance literature:: In isopropyl alcohol; for 72h; Heating;
DOI:10.1021/jm00088a010

Reference yield:

: 96-32-2
bromoacetic acid methyl ester

: 107332-67-2
N-benzyl-N-(2-p-hydroxyphenoxyethyl)-3-o-fluorophenoxy-2-hydroxypropylamine

: 107332-68-3
methyl 2-p-(2-[N-benzyl-(3-o-fluorophenoxy-2-hydroxypropyl)amino]ethoxy)phenoxyacetate

Guidance literature:: With potassium carbonate; potassium iodide; In acetone; for 24h; Heating;
DOI:10.1021/jm00088a010

Reference yield:

: 107332-67-2
N-benzyl-N-(2-p-hydroxyphenoxyethyl)-3-o-fluorophenoxy-2-hydroxypropylamine

: 107332-70-7
(4-{2-[3-(2-Fluoro-phenoxy)-2-hydroxy-propylamino]-ethoxy}-phenoxy)-acetic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃, KI / acetone / 24 h / Heating

2: H₂, AcOH / 10percent Pd/C / methanol / 48 h / 60 °C / 15001.2 Torr

With hydrogen; potassium carbonate; acetic acid; potassium iodide; palladium on activated charcoal; In methanol; acetone;
DOI:10.1021/jm00088a010