ethyl 3-chloro-2-(2-ethoxy-2-oxoethyl)-4,6-dimethoxybenzoate

Base Information

• Chemical Name: ethyl 3-chloro-2-(2-ethoxy-2-oxoethyl)-4,6-dimethoxybenzoate
• CAS No.: 1321611-26-0
• Molecular Formula: C₁₅H₁₉ClO₆
• Molecular Weight: 330.765
• Mol file: 1321611-26-0.mol

Synonyms:ethyl 3-chloro-2-(2-ethoxy-2-oxoethyl)-4,6-dimethoxybenzoate

Chemical Property of ethyl 3-chloro-2-(2-ethoxy-2-oxoethyl)-4,6-dimethoxybenzoate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of ethyl 3-chloro-2-(2-ethoxy-2-oxoethyl)-4,6-dimethoxybenzoate

There total 1 articles about ethyl 3-chloro-2-(2-ethoxy-2-oxoethyl)-4,6-dimethoxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

2-ethoxycarbonylmethyl-4,6-dimethoxybenzoic acid ethyl ester (6512-27-2) → ethyl 3-chloro-2-(2-ethoxy-2-oxoethyl)-4,6-dimethoxybenzoate (1321611-26-0)

Guidance literature:

With N-chloro-succinimide; In N,N-dimethyl-formamide; at 20 ℃; for 24h;

DOI:10.1080/10286020.2011.572552

Reference yield: 90.0%

ethyl 3-chloro-2-(2-ethoxy-2-oxoethyl)-4,6-dimethoxybenzoate (1321611-26-0) → 2-(carboxymethyl)-3-chloro-4,6-dimethoxybenzoic acid (75177-70-7)

Guidance literature:

ethyl 3-chloro-2-(2-ethoxy-2-oxoethyl)-4,6-dimethoxybenzoate; With potassium hydroxide; In ethanol; for 3h; Reflux;

With hydrogenchloride; In water; Cooling;

DOI:10.1080/10286020.2011.572552

upstream raw materials:

2-ethoxycarbonylmethyl-4,6-dimethoxybenzoic acid ethyl ester

Downstream raw materials:

2-(carboxymethyl)-3-chloro-4,6-dimethoxybenzoic acid