(2-ethyl-1,1-dioxo-1λ⁶-isothiazolidin-5-yl)-(3-methoxy-4-methoxymethoxy-phenyl)-methanol

Base Information

• Chemical Name: (2-ethyl-1,1-dioxo-1λ⁶-isothiazolidin-5-yl)-(3-methoxy-4-methoxymethoxy-phenyl)-methanol
• CAS No.: 158090-39-2
• Molecular Formula: C₁₅H₂₃NO₆S
• Molecular Weight: 345.417

Synonyms:(2-ethyl-1,1-dioxo-1λ⁶-isothiazolidin-5-yl)-(3-methoxy-4-methoxymethoxy-phenyl)-methanol

Chemical Property of (2-ethyl-1,1-dioxo-1λ⁶-isothiazolidin-5-yl)-(3-methoxy-4-methoxymethoxy-phenyl)-methanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2-ethyl-1,1-dioxo-1λ⁶-isothiazolidin-5-yl)-(3-methoxy-4-methoxymethoxy-phenyl)-methanol

There total 2 articles about (2-ethyl-1,1-dioxo-1λ⁶-isothiazolidin-5-yl)-(3-methoxy-4-methoxymethoxy-phenyl)-methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-methoxy-4-methoxymethoxy-benzaldehyde (5533-00-6) + N-ethyl-1,2-isothiazolidine-1,1-dioxide (73343-04-1) → (2-ethyl-1,1-dioxo-1λ6-isothiazolidin-5-yl)-(3-methoxy-4-methoxymethoxy-phenyl)-methanol (158090-39-2)

Guidance literature:

With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h;

DOI:10.1021/jm9906015

Reference yield:

N1-ethyl-3-chloro-1-propanesulfonamide (216487-29-5) → (2-ethyl-1,1-dioxo-1λ6-isothiazolidin-5-yl)-(3-methoxy-4-methoxymethoxy-phenyl)-methanol (158090-39-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 93 percent / NaH / tetrahydrofuran / 0.5 h / Heating

2: diisopropylamine; BuLi; hexamethylphosphamide / hexane; tetrahydrofuran / 0.5 h / -78 °C

With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; sodium hydride; diisopropylamine; In tetrahydrofuran; hexane; 1: Cyclization / 2: Addition;

DOI:10.1021/jm9906015

Reference yield: 13.0%

(2-ethyl-1,1-dioxo-1λ6-isothiazolidin-5-yl)-(3-methoxy-4-methoxymethoxy-phenyl)-methanol (158090-39-2) → 4-[2-Ethyl-1,1-dioxo-1λ6-isothiazolidin-(5E)-ylidenemethyl]-2-methoxy-phenol

Guidance literature:

With toluene-4-sulfonic acid; In toluene; for 0.5h; Heating;

DOI:10.1021/jm9906015

upstream raw materials:

3-methoxy-4-methoxymethoxy-benzaldehyde

N-ethyl-1,2-isothiazolidine-1,1-dioxide

N₁-ethyl-3-chloro-1-propanesulfonamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 158090-39-2 (2-ethyl-1,1-dioxo-1λ⁶-isothiazolidin-5-yl)-(3-methoxy-4-methoxymethoxy-phenyl)-methanol

Send

Send

Metric Ton KG G Pound L ML

Send

Send