N-Succinimidyl 6-(3-Maleimidopropionamido) Hexanoate

Base Information

Chemical Name:N-Succinimidyl 6-(3-Maleimidopropionamido) Hexanoate
CAS No.:367927-39-7
Molecular Formula:C₁₇H₂₁N₃O₇
Molecular Weight:379.37
Hs Code.:
European Community (EC) Number:686-180-7
DSSTox Substance ID:DTXSID80400226
Nikkaji Number:J1.988.601H
Wikidata:Q82203089
Mol file:367927-39-7.mol

Synonyms:367927-39-7;SMPH Crosslinker;N-Succinimidyl 6-(3-Maleimidopropionamido) Hexanoate;2,5-Dioxopyrrolidin-1-yl 6-(3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido)hexanoate;succinimidyl-6-(beta-maleimidopropionamido)hexanoate;SMPH;2,5-dioxopyrrolidin-1-yl 6-[3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido]hexanoate;(2,5-dioxopyrrolidin-1-yl) 6-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]hexanoate;SCHEMBL109173;LCZC1636;DTXSID80400226;MFCD01863460;AS-69227;BP-22646;HY-124318;A6332;CS-0086198;FT-0604064;D96043;SMPH (succinimidyl-6-((b-maleimidopropionamido)hexanoate);2,5-Dioxopyrrolidin-1-yl6-(3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido)hexanoate;6-[[3-[(2,5-Dioxo-2,5-dihydro-1H-pyrrole)-1-yl]-1-oxopropyl]amino]hexanoic acid 2,5-dioxo-1-pyrrolidinyl ester

Suppliers and Price of N-Succinimidyl 6-(3-Maleimidopropionamido) Hexanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-Succinimidyl6-(3-Maleimidopropionamido)Hexanoate
100mg
$ 175.00

Medical Isotopes, Inc.
N-Succinimidyl6-(3-Maleimidopropionamido)Hexanoate
50 mg
$ 1640.00

BroadPharm
SMPHCrosslinker 97%
1 G
$ 1485.00

American Custom Chemicals Corporation
N-SUCCINIMIDYL-6-(3-MALEIMIDOPROPIONAMIDO) HEXANOATE 95.00%
5MG
$ 498.96

AK Scientific
N-Succinimidyl6-(3-maleimidopropionamido)hexanoate
250mg
$ 583.00

Total 12 raw suppliers

Chemical Property of N-Succinimidyl 6-(3-Maleimidopropionamido) Hexanoate

Chemical Property:

PSA：130.16000
LogP:-0.14800
XLogP3:-1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:11
Exact Mass:379.13795002
Heavy Atom Count:27
Complexity:652

Purity/Quality:

97% ^*data from raw suppliers

N-Succinimidyl6-(3-Maleimidopropionamido)Hexanoate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=O)N(C1=O)OC(=O)CCCCCNC(=O)CCN2C(=O)C=CC2=O
Description SMPH Crosslinker is a non-cleavable, water soluble crosslinker containing a maleimide and NHS ester group. The maleimide is able to react with thiol groups between pH 6.5 to 7.5 to form thiolester bonds. NHS ester groups are reactive toward primary amines.
Uses A sulfhydryl and amino reactive heterobifunctional crosslinking reagent.Spacer Arm: 14.3 Angstroms A sulfhydryl and amino reactive heterobifunctional crosslinking reagent. Spacer Arm: 14.3 Angstroms

Technology Process of N-Succinimidyl 6-(3-Maleimidopropionamido) Hexanoate

There total 2 articles about N-Succinimidyl 6-(3-Maleimidopropionamido) Hexanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 55750-62-4
3-maleimidopropionic acid N-hydroxysuccinimide ester

: 60-32-2,93208-38-9
6-aminohexanoic acid

: 367927-39-7
succinimidyl 6-(beta-maleimideopropionamido)hexanoate

Guidance literature:: 3-maleimidopropionic acid N-hydroxysuccinimide ester; 6-aminohexanoic acid; In acetonitrile; at 70 ℃; Inert atmosphere;

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In acetonitrile; at 0 - 21 ℃;