Technology Process of C27H31NO5
There total 3 articles about C27H31NO5 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
Noyori's catalyst; [RhCl2(p-cymene)]2; tetrabutyl-ammonium chloride; sodium formate;
In
dichloromethane;
at 30 ℃;
for 72h;
optical yield given as %de;
DOI:10.1002/anie.201200248
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 9-epi-9-amino-9-deoxyquinine; trifluoroacetic acid / toluene / 42 h / 60 °C
2: Noyori's catalyst; [RhCl2(p-cymene)]2; tetrabutyl-ammonium chloride; sodium formate / dichloromethane / 72 h / 30 °C
With
9-epi-9-amino-9-deoxyquinine; Noyori's catalyst; [RhCl2(p-cymene)]2; tetrabutyl-ammonium chloride; sodium formate; trifluoroacetic acid;
In
dichloromethane; toluene;
1: Diels-Alder reaction;
DOI:10.1002/anie.201200248
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 9-epi-9-amino-9-deoxyquinine; trifluoroacetic acid / toluene / 42 h / 60 °C
2: Noyori's catalyst; [RhCl2(p-cymene)]2; tetrabutyl-ammonium chloride; sodium formate / dichloromethane / 72 h / 30 °C
With
9-epi-9-amino-9-deoxyquinine; Noyori's catalyst; [RhCl2(p-cymene)]2; tetrabutyl-ammonium chloride; sodium formate; trifluoroacetic acid;
In
dichloromethane; toluene;
1: Diels-Alder reaction;
DOI:10.1002/anie.201200248