[((E)-4-phenylbut-3-en-2-ylidene)amino]hydroxide

Base Information

• Chemical Name: [((E)-4-phenylbut-3-en-2-ylidene)amino]hydroxide
• CAS No.: 61210-87-5
• Molecular Formula: C₁₀H₁₁NO
• Molecular Weight: 161.203
• Mol file: 61210-87-5.mol

Synonyms:[((E)-4-phenylbut-3-en-2-ylidene)amino]hydroxide

Chemical Property of [((E)-4-phenylbut-3-en-2-ylidene)amino]hydroxide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of [((E)-4-phenylbut-3-en-2-ylidene)amino]hydroxide

There total 4 articles about [((E)-4-phenylbut-3-en-2-ylidene)amino]hydroxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.7%

(E)-benzalacetone (1896-62-4) → [((E)-4-phenylbut-3-en-2-ylidene)amino]hydroxide (61210-87-5)

Guidance literature:

With hydroxylamine; In dichloromethane; at 20 ℃; for 16h; Inert atmosphere;

DOI:10.1002/asia.200900311

Reference yield: 82.0%

1-Phenylbut-1-en-3-one (122-57-6) → [((E)-4-phenylbut-3-en-2-ylidene)amino]hydroxide (61210-87-5)

Guidance literature:

With sodium hydroxide; hydroxylamine hydrochloride; In ethanol; for 0.0833333h; Heating;

DOI:10.1021/ja00293a041

Reference yield:

ethyl (E)-1-phenylbut-1-en-3-ol (36004-04-3) → [((E)-4-phenylbut-3-en-2-ylidene)amino]hydroxide (61210-87-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; oxygen / tert-butyl methyl ether / 16 h / 30 °C / pH 5 / Enzymatic reaction

2: sodium hydroxide; hydroxylamine hydrochloride / water; ethanol / Reflux

With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; hydroxylamine hydrochloride; oxygen; sodium hydroxide; In ethanol; tert-butyl methyl ether; water;

DOI:10.1002/cbic.201900473

upstream raw materials:

1-Phenylbut-1-en-3-one

(E)-benzalacetone

ethyl (E)-1-phenylbut-1-en-3-ol

Downstream raw materials:

4-phenyl-but-3-en-2-one O-morpholin-4-ylmethyl-oxime

C₁₃H₁₉NOSi

(E)-2-<<('4-methylphenyl)sulfonyl>imino>-4-phenyl-3-butene

(RS)-1-methyl-3-phenylpropylamine