5-{4-[3-chloro-4-(3-fluoro-α,α-d2-benzyloxy)-phenylamino]-quinazolin-6-yl}-furan-2-carboxylic acid methoxy-methyl-amide

Base Information

Chemical Name:5-{4-[3-chloro-4-(3-fluoro-α,α-d2-benzyloxy)-phenylamino]-quinazolin-6-yl}-furan-2-carboxylic acid methoxy-methyl-amide
CAS No.:1009307-51-0
Molecular Formula:C₂₈H₂₂ClFN₄O₄
Molecular Weight:534.943
Hs Code.:

Synonyms:5-{4-[3-chloro-4-(3-fluoro-α,α-d2-benzyloxy)-phenylamino]-quinazolin-6-yl}-furan-2-carboxylic acid methoxy-methyl-amide

Suppliers and Price of 5-{4-[3-chloro-4-(3-fluoro-α,α-d2-benzyloxy)-phenylamino]-quinazolin-6-yl}-furan-2-carboxylic acid methoxy-methyl-amide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5-{4-[3-chloro-4-(3-fluoro-α,α-d2-benzyloxy)-phenylamino]-quinazolin-6-yl}-furan-2-carboxylic acid methoxy-methyl-amide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5-{4-[3-chloro-4-(3-fluoro-α,α-d2-benzyloxy)-phenylamino]-quinazolin-6-yl}-furan-2-carboxylic acid methoxy-methyl-amide

There total 1 articles about 5-{4-[3-chloro-4-(3-fluoro-α,α-d2-benzyloxy)-phenylamino]-quinazolin-6-yl}-furan-2-carboxylic acid methoxy-methyl-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1009307-50-9
5-(methoxy(methyl)carbamoyl)furan-2-ylboronic acid

: 1009307-48-5
[3-chloro-4-(3-fluoro-α,α-d2-benzyloxy)phenyl](6-iodoquinazolin-4-yl)amine

: 1009307-51-0
5-{4-[3-chloro-4-(3-fluoro-α,α-d2-benzyloxy)-phenylamino]-quinazolin-6-yl}-furan-2-carboxylic acid methoxy-methyl-amide

Guidance literature:: With triethylamine; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In ethanol; for 2h; Heating / reflux;

Reference yield: 100.0%

: 1009307-51-0
5-{4-[3-chloro-4-(3-fluoro-α,α-d2-benzyloxy)-phenylamino]-quinazolin-6-yl}-furan-2-carboxylic acid methoxy-methyl-amide

: 1009307-52-1
5-{4-[3-chloro-4-(3-fluoro-α,α-d2-benzyloxy)phenylamino]quinazolin-6-yl}furan-2-carbaldehyde-d

Guidance literature:: 5-{4-[3-chloro-4-(3-fluoro-α,α-d2-benzyloxy)-phenylamino]-quinazolin-6-yl}-furan-2-carboxylic acid methoxy-methyl-amide; With lithium aluminium deuteride; In tetrahydrofuran; at 5 ℃; for 1h;

With deuteriated sodium hydroxide; water-d2; In tetrahydrofuran;