N-(4-amino-5-chloro-2-methoxyphenyl)-1-<(4-hydroxyphenyl)methyl>-4-piperidinecarboxamide

Base Information

Chemical Name:N-(4-amino-5-chloro-2-methoxyphenyl)-1-<(4-hydroxyphenyl)methyl>-4-piperidinecarboxamide
CAS No.:86956-19-6
Molecular Formula:C₂₀H₂₄ClN₃O₃
Molecular Weight:389.882
Hs Code.:

Synonyms:N-(4-amino-5-chloro-2-methoxyphenyl)-1-<(4-hydroxyphenyl)methyl>-4-piperidinecarboxamide

Suppliers and Price of N-(4-amino-5-chloro-2-methoxyphenyl)-1-<(4-hydroxyphenyl)methyl>-4-piperidinecarboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(4-amino-5-chloro-2-methoxyphenyl)-1-<(4-hydroxyphenyl)methyl>-4-piperidinecarboxamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(4-amino-5-chloro-2-methoxyphenyl)-1-<(4-hydroxyphenyl)methyl>-4-piperidinecarboxamide

There total 4 articles about N-(4-amino-5-chloro-2-methoxyphenyl)-1-<(4-hydroxyphenyl)methyl>-4-piperidinecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

: 86956-47-0
N-(5-chloro-2-methoxy-4-nitrophenyl)-1-<<4-(phenylmethoxy)phenyl>methyl>-4-piperidinecarboxamide

: 86956-19-6
N-(4-amino-5-chloro-2-methoxyphenyl)-1-<(4-hydroxyphenyl)methyl>-4-piperidinecarboxamide

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; Ambient temperature;
DOI:10.1021/jm00366a017

Reference yield:

: 69082-73-1
N-(5-chloro-2-methoxyphenyl)-4-piperidinecarboxamide

: 86956-19-6
N-(4-amino-5-chloro-2-methoxyphenyl)-1-<(4-hydroxyphenyl)methyl>-4-piperidinecarboxamide

Guidance literature:: Multi-step reaction with 3 steps

1: 82 percent / fuming HNO₃, H₂SO₄ / acetic acid / 2 h

2: 54 percent

3: 37 percent / H₂ / 10percent Pd/C / ethanol / Ambient temperature

With sulfuric acid; hydrogen; nitric acid; palladium on activated charcoal; In ethanol; acetic acid;
DOI:10.1021/jm00366a017

Reference yield:

: 69082-75-3
N-(5-chloro-2-methoxy-4-nitrophenyl)-4-piperidinecarboxamide

: 86956-19-6
N-(4-amino-5-chloro-2-methoxyphenyl)-1-<(4-hydroxyphenyl)methyl>-4-piperidinecarboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: 54 percent

2: 37 percent / H₂ / 10percent Pd/C / ethanol / Ambient temperature

With hydrogen; palladium on activated charcoal; In ethanol;
DOI:10.1021/jm00366a017