2-methylpropyl 2-[4-(trifluoromethoxy)phenyl]-1,3-thiazole-4-carboxylate

Base Information

Chemical Name:2-methylpropyl 2-[4-(trifluoromethoxy)phenyl]-1,3-thiazole-4-carboxylate
CAS No.:1366407-10-4
Molecular Formula:C₁₅H₁₄F₃NO₃S
Molecular Weight:345.342
Hs Code.:

Synonyms:2-methylpropyl 2-[4-(trifluoromethoxy)phenyl]-1,3-thiazole-4-carboxylate

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Chemical Property of 2-methylpropyl 2-[4-(trifluoromethoxy)phenyl]-1,3-thiazole-4-carboxylate

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Technology Process of 2-methylpropyl 2-[4-(trifluoromethoxy)phenyl]-1,3-thiazole-4-carboxylate

There total 1 articles about 2-methylpropyl 2-[4-(trifluoromethoxy)phenyl]-1,3-thiazole-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1366407-10-4
2-methylpropyl 2-[4-(trifluoromethoxy)phenyl]-1,3-thiazole-4-carboxylate

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; caesium carbonate; In ethanol; water; toluene; at 100 ℃; for 3h;

Reference yield:

: 1366407-10-4
2-methylpropyl 2-[4-(trifluoromethoxy)phenyl]-1,3-thiazole-4-carboxylate

: 1231169-72-4
{2-[4-(trifluoromethoxy)phenyl]-1,3-thiazol-4-yl}methanol

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃; for 0.5h;

Reference yield:

: 1366407-10-4
2-methylpropyl 2-[4-(trifluoromethoxy)phenyl]-1,3-thiazole-4-carboxylate

: 1183405-42-6
2-[4-(trifluoromethoxy)phenyl]-1,3-thiazole-4-carbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: lithium aluminium tetrahydride / tetrahydrofuran / 0.5 h / 20 °C

2: 2-iodoxybenzoic acid / dimethyl sulfoxide / 20 °C

With lithium aluminium tetrahydride; 2-iodoxybenzoic acid; In tetrahydrofuran; dimethyl sulfoxide;