4-phenyl-4-((4-carboethoxymethylpiperazin-1-yl)carboxamido)piperidine hydrochloric acid salt

Base Information

Chemical Name:4-phenyl-4-((4-carboethoxymethylpiperazin-1-yl)carboxamido)piperidine hydrochloric acid salt
CAS No.:209667-53-8
Molecular Formula:C₂₀H₂₉N₃O₃*ClH
Molecular Weight:395.93
Hs Code.:

Synonyms:4-phenyl-4-((4-carboethoxymethylpiperazin-1-yl)carboxamido)piperidine hydrochloric acid salt

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Chemical Property of 4-phenyl-4-((4-carboethoxymethylpiperazin-1-yl)carboxamido)piperidine hydrochloric acid salt

Chemical Property:

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Technology Process of 4-phenyl-4-((4-carboethoxymethylpiperazin-1-yl)carboxamido)piperidine hydrochloric acid salt

There total 4 articles about 4-phenyl-4-((4-carboethoxymethylpiperazin-1-yl)carboxamido)piperidine hydrochloric acid salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 209667-67-4
1-t-butoxycarbonyl-4-phenyl-4-((4-carboethoxymethylpiperazin-1-yl)carboxamido)piperidine

: 209667-53-8
4-phenyl-4-((4-carboethoxymethylpiperazin-1-yl)carboxamido)piperidine hydrochloric acid salt

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; dichloromethane; for 5h;

Reference yield:

: 167262-68-2
N-(t-butyloxycarbonyl)-4-phenylpiperidine-4-carboxylic acid

: 209667-53-8
4-phenyl-4-((4-carboethoxymethylpiperazin-1-yl)carboxamido)piperidine hydrochloric acid salt

Guidance literature:: Multi-step reaction with 2 steps

1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / dichloromethane / 20 h

2: hydrogenchloride / 1,4-dioxane; dichloromethane / 5 h

With hydrogenchloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; dichloromethane;

Reference yield:

: 4-phenyl-4-piperidinecarboxylic acid 4-methylbenzenesulfonate

: 209667-53-8
4-phenyl-4-((4-carboethoxymethylpiperazin-1-yl)carboxamido)piperidine hydrochloric acid salt

Guidance literature:: Multi-step reaction with 3 steps

1: N-ethyl-N,N-diisopropylamine / DMF (N,N-dimethyl-formamide) / 20 h

2: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / dichloromethane / 20 h

3: hydrogenchloride / 1,4-dioxane; dichloromethane / 5 h

With hydrogenchloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; DMF (N,N-dimethyl-formamide); dichloromethane;