Mosher amide of trans-4-carboxy-D-proline dimethyl ester

Base Information

Chemical Name:Mosher amide of trans-4-carboxy-D-proline dimethyl ester
CAS No.:130830-82-9
Molecular Formula:C₁₈H₂₀F₃NO₆
Molecular Weight:403.355
Hs Code.:

Synonyms:Mosher amide of trans-4-carboxy-D-proline dimethyl ester

Suppliers and Price of Mosher amide of trans-4-carboxy-D-proline dimethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Mosher amide of trans-4-carboxy-D-proline dimethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Mosher amide of trans-4-carboxy-D-proline dimethyl ester

There total 7 articles about Mosher amide of trans-4-carboxy-D-proline dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 130830-67-0
N-(benzyloxycarbonyl)-trans-4-cyano-D-proline ethyl ester

: 130830-82-9
Mosher amide of trans-4-carboxy-D-proline dimethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 94 percent / HCl / 96 h

2: H₂ / 10percent Pd/C / ethanol / 0.5 h / 2585.7 Torr

3: 16 h / Ambient temperature

With hydrogenchloride; hydrogen; palladium on activated charcoal; In ethanol;
DOI:10.1021/jm00106a037

Reference yield:

: 130930-27-7
(2R,4R)-2-ethoxycarbonyl-4-hydroxy-N-(benzyloxycarbonyl)pyrrolidine

: 130830-82-9
Mosher amide of trans-4-carboxy-D-proline dimethyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 92 percent / pyridine / CHCl₃ / 168 h / Ambient temperature

2: 72 percent / dimethylsulfoxide / 4 h / 80 °C

3: 94 percent / HCl / 96 h

4: H₂ / 10percent Pd/C / ethanol / 0.5 h / 2585.7 Torr

5: 16 h / Ambient temperature

With pyridine; hydrogenchloride; hydrogen; palladium on activated charcoal; In ethanol; chloroform; dimethyl sulfoxide;
DOI:10.1021/jm00106a037

Reference yield:

: 130830-71-6
N-(benzyloxycarbonyl)-trans-4-carboxy-D-proline dimethyl ester

: 130830-82-9
Mosher amide of trans-4-carboxy-D-proline dimethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / 10percent Pd/C / ethanol / 0.5 h / 2585.7 Torr

2: 16 h / Ambient temperature

With hydrogen; palladium on activated charcoal; In ethanol;
DOI:10.1021/jm00106a037