4-iodomethyl-3,5-dimethylphenyl ethyl carbonate

Base Information

• Chemical Name: 4-iodomethyl-3,5-dimethylphenyl ethyl carbonate
• CAS No.: 1185756-57-3
• Molecular Formula: C₁₂H₁₅IO₃
• Molecular Weight: 334.154
• Mol file: 1185756-57-3.mol

Synonyms:4-iodomethyl-3,5-dimethylphenyl ethyl carbonate

Chemical Property of 4-iodomethyl-3,5-dimethylphenyl ethyl carbonate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 4-iodomethyl-3,5-dimethylphenyl ethyl carbonate

There total 1 articles about 4-iodomethyl-3,5-dimethylphenyl ethyl carbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

O-ethoxycarbonyl-3,5-dimethyl-4-chloromethylphenol (54373-50-1) → 4-iodomethyl-3,5-dimethylphenyl ethyl carbonate (1185756-57-3)

Guidance literature:

With sodium iodide; In acetone; at 20 ℃; for 50h;

DOI:10.1016/j.tetasy.2009.06.004

Reference yield:

4-iodomethyl-3,5-dimethylphenyl ethyl carbonate (1185756-57-3) + 1,4-N,N-[(S)-1-phenylethyl]-piperazine-2,5-dione (158547-56-9) → C44H50N2O8 (1185756-58-4)

Guidance literature:

1,4-N,N-[(S)-1-phenylethyl]-piperazine-2,5-dione; With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; Inert atmosphere;

4-iodomethyl-3,5-dimethylphenyl ethyl carbonate; In tetrahydrofuran; diastereoselective reaction; Further stages; Inert atmosphere;

DOI:10.1016/j.tetasy.2009.06.004

upstream raw materials:

O-ethoxycarbonyl-3,5-dimethyl-4-chloromethylphenol

Downstream raw materials:

C₄₄H₅₀N₂O₈