(3S)-methyl 3-(4-(5-(4-(trifluoromethyl)phenyl)-2,3-dihydro-1H-inden-1-yloxy)phenyl)hex-4-ynoate

Base Information

Chemical Name:(3S)-methyl 3-(4-(5-(4-(trifluoromethyl)phenyl)-2,3-dihydro-1H-inden-1-yloxy)phenyl)hex-4-ynoate
CAS No.:929713-36-0
Molecular Formula:C₂₉H₂₅F₃O₃
Molecular Weight:478.511
Hs Code.:

Synonyms:(3S)-methyl 3-(4-(5-(4-(trifluoromethyl)phenyl)-2,3-dihydro-1H-inden-1-yloxy)phenyl)hex-4-ynoate

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Chemical Property of (3S)-methyl 3-(4-(5-(4-(trifluoromethyl)phenyl)-2,3-dihydro-1H-inden-1-yloxy)phenyl)hex-4-ynoate

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Technology Process of (3S)-methyl 3-(4-(5-(4-(trifluoromethyl)phenyl)-2,3-dihydro-1H-inden-1-yloxy)phenyl)hex-4-ynoate

There total 1 articles about (3S)-methyl 3-(4-(5-(4-(trifluoromethyl)phenyl)-2,3-dihydro-1H-inden-1-yloxy)phenyl)hex-4-ynoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 929713-35-9
(3S)-methyl 3-(4-(5-bromo-2,3-dihydro-1H-inden-1-yloxy)phenyl)hex-4-ynoate

: 128796-39-4
4-trifluoromethylphenylboronic acid

: 929713-36-0
(3S)-methyl 3-(4-(5-(4-(trifluoromethyl)phenyl)-2,3-dihydro-1H-inden-1-yloxy)phenyl)hex-4-ynoate

Guidance literature:: With cesium fluoride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; at 95 ℃; for 8.05h;

Reference yield:

: 929713-36-0
(3S)-methyl 3-(4-(5-(4-(trifluoromethyl)phenyl)-2,3-dihydro-1H-inden-1-yloxy)phenyl)hex-4-ynoate

: (3S)-3-(4-(5-(4-(trifluoromethyl)phenyl)-2,3-dihydro-1H-inden-1-yloxy)phenyl)hex-4-ynoic acid

Guidance literature:: (3S)-methyl 3-(4-(5-(4-(trifluoromethyl)phenyl)-2,3-dihydro-1H-inden-1-yloxy)phenyl)hex-4-ynoate; With methanol; sodium hydroxide; water; In tetrahydrofuran; at 20 ℃; for 2h;

With hydrogenchloride; In tetrahydrofuran; water;