(1,3-DIOXOLAN-2-YLETHYL)MAGNESIUM BROMIDE

Base Information

• Chemical Name: (1,3-DIOXOLAN-2-YLETHYL)MAGNESIUM BROMIDE
• CAS No.: 37610-80-3
• Molecular Formula: C5H9 Br Mg O2
• Molecular Weight: 205.334
• Hs Code.: 2932999099
• Mol file: 37610-80-3.mol

Synonyms:1,3-Dioxolane,2-ethyl-, magnesium complex; Magnesium, bromo[2-(1,3-dioxolan-2-yl)ethyl-C,O]-(8CI); Magnesium, bromo[2-(1,3-dioxolan-2-yl)ethyl]-;3-(Ethylenedioxypropyl)magnesium bromide; [2-(1,3-Dioxolan-2-yl)ethyl]magnesiumbromide

Chemical Property of (1,3-DIOXOLAN-2-YLETHYL)MAGNESIUM BROMIDE

Chemical Property:

• PSA: 18.46000
• LogP: 1.56260

Purity/Quality:

99% ^*data from raw suppliers

2-(1,3-Dioxolan-2-yl)ethylmagnesiumbromide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (1,3-DIOXOLAN-2-YLETHYL)MAGNESIUM BROMIDE

There total 2 articles about (1,3-DIOXOLAN-2-YLETHYL)MAGNESIUM BROMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-bromo-2-(2-ethyl)dioxolane (18742-02-4) → 1,3-dioxolan-2-ylethylmagnesium bromide (37610-80-3)

Guidance literature:

With magnesium; In tetrahydrofuran;

DOI:10.1016/0040-4020(82)80080-X

Reference yield:

2-bromo-2-(2-ethyl)dioxolane (18742-02-4) + magnesium (7439-95-4) → 1,3-dioxolan-2-ylethylmagnesium bromide (37610-80-3)

Guidance literature:

iodine; In tetrahydrofuran; at 20 - 50 ℃; for 0.5h;

Reference yield: 99.0%

1,3-dioxolan-2-ylethylmagnesium bromide (37610-80-3) + (R)-benzyl glycidol (14618-80-5) → C15H22O4 (944241-93-4)

Guidance literature:

With copper(I) bromide dimethylsulfide complex; In tetrahydrofuran; at -78 ℃; for 2h;

DOI:10.1016/j.tetlet.2007.04.076

upstream raw materials:

2-bromo-2-(2-ethyl)dioxolane

magnesium

Downstream raw materials:

1-(3-benzyl-2-ethyl-3H-imidazol-4-yl)-3-[1,3]dioxolan-2-yl-propan-1-ol

1-(3-benzyl-2-isopropyl-3H-imidazol-4-yl)-3-[1,3]dioxolan-2-yl-propan-1-ol

1-(3-benzyl-2-tert-butyl-3H-imidazol-4-yl)-3-[1,3]dioxolan-2-yl-propan-1-ol

1-(3-benzyl-2-methyl-3H-imidazol-4-yl)-3-[1,3]dioxolan-2-yl-propan-1-ol

Refernces

• 1、 -. "METHODS FOR PREPARING TYROSINE RECEPTOR KINASE INHIBITORS". Paragraph 00460-00461. . Retrieved 2021/10/22.
• 2、 Tsuie, Barbara,Reddinger, Jerry L.,Sotzing, Gregory A.,Soloducho, Jadwiga,Katritzky, Alan R.,Reynolds, John R.. "Electroactive and luminescent polymers: New fluorene-heterocycle-based hybrids". . p. 2189 - 2200. Retrieved 2007/10/03.