6-[4-(3-{[2-hydroxy-3-(2-methylphenoxy)propyl]amino}propionamido)phenyl]-4,5-dihydro-3(2H)-pyridazinone

Base Information

Chemical Name:6-[4-(3-{[2-hydroxy-3-(2-methylphenoxy)propyl]amino}propionamido)phenyl]-4,5-dihydro-3(2H)-pyridazinone
CAS No.:111794-09-3
Molecular Formula:C₂₃H₂₈N₄O₄
Molecular Weight:424.5
Hs Code.:

Synonyms:6-[4-(3-{[2-hydroxy-3-(2-methylphenoxy)propyl]amino}propionamido)phenyl]-4,5-dihydro-3(2H)-pyridazinone

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Chemical Property of 6-[4-(3-{[2-hydroxy-3-(2-methylphenoxy)propyl]amino}propionamido)phenyl]-4,5-dihydro-3(2H)-pyridazinone

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Technology Process of 6-[4-(3-{[2-hydroxy-3-(2-methylphenoxy)propyl]amino}propionamido)phenyl]-4,5-dihydro-3(2H)-pyridazinone

There total 6 articles about 6-[4-(3-{[2-hydroxy-3-(2-methylphenoxy)propyl]amino}propionamido)phenyl]-4,5-dihydro-3(2H)-pyridazinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 111794-45-7
6-<4-<3-amino>propionamido>phenyl>-4,5-dihydro-3(2H)-pyridazinone

: 111794-09-3
6-[4-(3-{[2-hydroxy-3-(2-methylphenoxy)propyl]amino}propionamido)phenyl]-4,5-dihydro-3(2H)-pyridazinone

Guidance literature:: With hydrogen; palladium dihydroxide; In acetic acid; for 12h;
DOI:10.1021/jm00397a013

Reference yield:

: 2210-79-9
o-Cresyl glycidyl ether

: 111794-09-3
6-[4-(3-{[2-hydroxy-3-(2-methylphenoxy)propyl]amino}propionamido)phenyl]-4,5-dihydro-3(2H)-pyridazinone

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / propan-1-ol / 16 h / Heating

2: 3.1 g / H₂ / palladium hydroxide on carbon / acetic acid / 12 h

With hydrogen; palladium dihydroxide; In propan-1-ol; acetic acid;
DOI:10.1021/jm00397a013

Reference yield:

: 95-48-7,77504-84-8
ortho-cresol

: 111794-09-3
6-[4-(3-{[2-hydroxy-3-(2-methylphenoxy)propyl]amino}propionamido)phenyl]-4,5-dihydro-3(2H)-pyridazinone

Guidance literature:: Multi-step reaction with 3 steps

1: base

2: 75 percent / propan-1-ol / 16 h / Heating

3: 3.1 g / H₂ / palladium hydroxide on carbon / acetic acid / 12 h

With hydrogen; palladium dihydroxide; In propan-1-ol; acetic acid;
DOI:10.1021/jm00397a013