5-Methylpyrazine-2-carbohydrazide

Base Information

• Chemical Name: 5-Methylpyrazine-2-carbohydrazide
• CAS No.: 37545-33-8
• Molecular Formula: C6H8 N4 O
• Molecular Weight: 152.15
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID10588627
• Wikidata: Q82481418
• Mol file: 37545-33-8.mol

Synonyms:5-Methylpyrazine-2-carbohydrazide;37545-33-8;SCHEMBL1874036;DTXSID10588627;IBFMTDRAKYKXQS-UHFFFAOYSA-N;MFCD09742108;AKOS015842175;MCULE-4757388036;BS-28013;DB-069563;5-methylpyrazine-2-carboxylic acid hydrazide;EN300-1232849

Chemical Property of 5-Methylpyrazine-2-carbohydrazide

Chemical Property:

• PSA: 80.90000
• LogP: 0.47970
• XLogP3: -0.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 152.06981089
• Heavy Atom Count: 11
• Complexity: 150

Purity/Quality:

97% ^*data from raw suppliers

5-Methylpyrazine-2-carbohydrazide 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CN=C(C=N1)C(=O)NN

Technology Process of 5-Methylpyrazine-2-carbohydrazide

There total 3 articles about 5-Methylpyrazine-2-carbohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

2-methylpyrazin-5-carboxylic acid (5521-55-1) → 5-methyl-2-pyrazinecarboxylic acid hydrazide (37545-33-8)

Guidance literature:

With hydrazine hydrate; In ethanol; for 9h; Reflux;

DOI:10.14233/ajchem.2016.19860

Reference yield: 72.0%

5-methyl-2-pyrazine carboxylic acid ethyl ester (41110-34-3) → 5-methyl-2-pyrazinecarboxylic acid hydrazide (37545-33-8)

Guidance literature:

With hydrazine hydrate; In ethanol; for 3h; Reflux;

DOI:10.14233/ajchem.2016.20011

Reference yield:

→ 5-methyl-2-pyrazinecarboxylic acid hydrazide (37545-33-8)

Guidance literature:

5-Methylpyrazinamid, Hydrazin;

DOI:10.1002/jps.2600610933

upstream raw materials:

2-methylpyrazin-5-carboxylic acid

5-methyl-2-pyrazine carboxylic acid ethyl ester