4,4',5,5'-tetramethoxy<2,2'-di-(5''-carbomethoxy-4''-phenyl-2''-thiazolyl)>-diphenyl disulfide

Base Information

• Chemical Name: 4,4',5,5'-tetramethoxy<2,2'-di-(5''-carbomethoxy-4''-phenyl-2''-thiazolyl)>-diphenyl disulfide
• CAS No.: 122347-93-7
• Molecular Formula: C₃₈H₃₂N₂O₈S₄
• Molecular Weight: 772.945
• Mol file: 122347-93-7.mol

Synonyms:4,4',5,5'-tetramethoxy<2,2'-di-(5''-carbomethoxy-4''-phenyl-2''-thiazolyl)>-diphenyl disulfide

Chemical Property of 4,4',5,5'-tetramethoxy<2,2'-di-(5''-carbomethoxy-4''-phenyl-2''-thiazolyl)>-diphenyl disulfide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,4',5,5'-tetramethoxy<2,2'-di-(5''-carbomethoxy-4''-phenyl-2''-thiazolyl)>-diphenyl disulfide

There total 1 articles about 4,4',5,5'-tetramethoxy<2,2'-di-(5''-carbomethoxy-4''-phenyl-2''-thiazolyl)>-diphenyl disulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 21.0%

6α-phenyl-7,7-dichloro-2,3-(2',3'-dimethoxybenzo)-1-thiaocem (78509-07-6) → 2-carbomethoxy-7,8-dimethoxy-3-phenyl-4,5-dihydro-1,4-benzothiazepine (81452-42-8) + 4-carbomethoxy-6,7-dimethoxy-3-phenylisoquinoline (110694-90-1) + 4,4',5,5'-tetramethoxy<2,2'-di-(5''-carbomethoxy-4''-phenyl-2''-thiazolyl)>-diphenyl disulfide (122347-93-7)

Guidance literature:

With potassium tert-butylate; In methanol; for 3h; Heating;

DOI:10.1016/S0040-4020(01)86087-7

Reference yield: 90.0%

4,4',5,5'-tetramethoxy<2,2'-di-(5''-carbomethoxy-4''-phenyl-2''-thiazolyl)>-diphenyl disulfide (122347-93-7) → 2-(5'-carbomethoxy-4'-phenyl-2'-thiazolyl)-4,5-dimethoxy-thiophenol (122347-94-8)

Guidance literature:

With hydrogenchloride; zinc; In dichloromethane; for 0.0833333h;

DOI:10.1016/S0040-4020(01)86087-7

Reference yield:

4,4',5,5'-tetramethoxy<2,2'-di-(5''-carbomethoxy-4''-phenyl-2''-thiazolyl)>-diphenyl disulfide (122347-93-7) → S-acetyl-(5'-carbomethoxy-4'-phenyl-2'-thiazolyl)-4,5-dimethoxy-thiophenol (122347-95-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / Zn/10percent HCl / CH₂Cl₂ / 0.08 h

2: 74 percent / TEA / benzene / 0.5 h

With hydrogenchloride; TEA; zinc; In dichloromethane; benzene;

DOI:10.1016/S0040-4020(01)86087-7

upstream raw materials:

6α-phenyl-7,7-dichloro-2,3-(2',3'-dimethoxybenzo)-1-thiaocem

Downstream raw materials:

2-(5'-carbomethoxy-4'-phenyl-2'-thiazolyl)-4,5-dimethoxy-thiophenol

S-acetyl-(5'-carbomethoxy-4'-phenyl-2'-thiazolyl)-4,5-dimethoxy-thiophenol