Technology Process of (-)-tetrahydrohumulone
There total 3 articles about (-)-tetrahydrohumulone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
dihydrogen peroxide; tris hydrochloride;
P450 heme domain mutant enzyme;
In
water; dimethyl sulfoxide;
pH=8.2;
Enzymatic reaction;
- Guidance literature:
-
tetrahydrohumulone;
With
(1R,2R)-cyclohex-4-ene-1,2-diamine;
In
isopropyl alcohol;
Resolution of racemate;
With
sulfuric acid;
In
hexanes; water;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: hydrogenchloride; hydrogen / palladium 10% on activated carbon / water; methanol / 3 h / 836.06 Torr
2: dihydrogen peroxide; tris hydrochloride / P450 heme domain mutant enzyme / water; dimethyl sulfoxide / pH 8.2 / Enzymatic reaction
With
hydrogenchloride; hydrogen; dihydrogen peroxide; tris hydrochloride;
palladium 10% on activated carbon; P450 heme domain mutant enzyme;
In
methanol; water; dimethyl sulfoxide;
